Malnutrition et épilepsie : des liens complexes

Crépin, Sabrina; Godet, Bertrand; Chassain, Benoît; Preux, Pierre‐Marie; Desport, Jean‐Claude

doi:10.1016/j.nupar.2008.04.003

Cited by 3 publications

(2 citation statements)

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“…Undernutrition appears to be able, through many mechanisms, most of which remain unexplored, to promote the onset of seizures and possibly epilepsy diseases. 36 Cerebral malaria is found in 8.3% of patients with known etiology in our series. Cerebral malaria has been identified as a potential cause of epilepsy in tropical regions.…”

Section: Discussionmentioning

confidence: 54%

Epidemiological and clinical features of epileptic patients in Goma, Democratic Republic of the Congo

Polepol¹,

Mukuku²,

Murhula³

et al. 2022

JNSK

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Introduction: Epilepsy is one of the most common neurological conditions but the majority of epileptic patients in sub-Saharan African countries do not receive appropriate treatment. In the Democratic Republic of the Congo (DRC), very few epidemiological studies have been conducted on epilepsy. The objective of this study was to describe socio-demographic characteristics, the type of epileptic seizures, and etiological factors of these seizures in a hospital cohort of epileptic patients followed at the Neuropsychiatric Hospital Center in Goma (in the DRC). Materials and methods: This was a cross-sectional study of 917 epileptic patients received in neurology consultation at the Neuropsychiatric Hospital Center in Goma (in the DRC) from January 1st, 2017 to December 31st, 2021. Results: The median age of patients was 16 years, the median age of the patients at onset of seizures was 13 years and the median time between onset of seizures and consultation was 8.0 months; 14.2% of had a family history of epilepsy. Generalized tonic-clonic seizures were the most frequent (76.7%), followed by motor focal impaired awareness seizures (5.2%) and non-motor focal aware seizures (3.6%). The etiologic factor was found in 444 (48.4%) patients and was dominated by chronic alcoholism (20.9%), neurocysticercosis (17.6%), meningitis (14.6%), malnutrition (11.3%), cerebral malaria (8.3%), and head injury (7.7%). Conclusion: This study provides an epidemiological overview of epilepsy in Goma city. The etiological factors and types of seizures will dictate the best possible treatment options.

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Section: Discussionmentioning

confidence: 54%

Epidemiological and clinical features of epileptic patients in Goma, Democratic Republic of the Congo

Polepol¹,

Mukuku²,

Murhula³

et al. 2022

JNSK

View full text Add to dashboard Cite

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Section: Discussionmentioning

confidence: 54%

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2022

JNSK

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per 1,000 persons) for active epilepsy and 16 per 1,000 persons (95% CI: 12.3-19.7 per 1,000 persons) for lifetime epilepsy, but this estimate was a median figure generated from these studies. These authors found that prevalence was highest in Central Africa at 30.2 per 1,000 people (95% CI: 6.2 to 66.7 per 1,000 persons) and that the prevalence of active epilepsy in rural areas was twice as high as in urban areas. 7 . More than 800,000 people are thought to have epilepsy in the Democratic Republic of the Congo (DRC), where very few epidemiological studies on this condition have been conducted. 8 Etiologies of epilepsy are diverse; they can be infectious, vascular, neoplastic, metabolic, genetic, or degenerative. Head injuries can also cause epilepsy immediately or several years later. Stroke and neurodegenerative diseases may be etiological factors of epilepsy in the elderly. 9 The present study aims to describe socio-demographic characteristics, the type of epileptic seizures, and etiological factors of these seizures in a hospital cohort of epileptic patients followed at the Neuropsychiatric Hospital Center in Goma (in the DRC). Materials and methods Study framework and designThis cross-sectional descriptive study was conducted at the Neuropsychiatric Hospital Center in Goma, North-Kivu province, the eastern DRC (city with about 2 million inhabitants). This hospital is the only hospital in North-Kivu province to provide specialized services in neuropsychiatry and has a bed capacity of 100 patients. Epilepsy prevalence in the community is unknown. Study population and variablesThe present study includes all adults and children admitted for epilepsy. We reviewed the admissions registry from January 1st, 2017 to December 31st, 2021 for patients diagnosed with epilepsy and/or a history of use of anti-epileptic drugs. Following data were collected using a form with a variety of variables and was obtained

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