Mallotus species from Vietnamese mountainous areas: phytochemistry and pharmacological activities

Abstract

The genus Mallotus belongs to Malphighiales order and Euphorbiaceae family.

Potentially antioxidant compounds indicated from Mallotus and Phyllanthus species fingerprints

“…DPPH • has an absorption band at 515 nm, which disappears upon reduction by an antiradical compound. The assay was carried out (11,12,19,22,27,29,32). The regression coefficients from PLS and O-PLS models, preprocessed with normalization and column centering, are also given.…”

“…For instance, the genus Mallotus has been used for the treatment of chronic hepatitis and enteritis [17,18], while the genus Phyllanthus has been used for kidney, urinary bladder, and intestinal infections, and for diabetes [19,20]. Recently, many studies were performed concerning the chemical components of Mallotus and Phyllanthus species and several pharmacologically active constituents were determined [12,[21][22][23][24][25]. Cytotoxic (Mallotus apelta [22]), antimicrobial (Mallotus peltalus [22], Phyllanthus emblica [24]), anti-inflammatory (Mallotus peltalus [22], Mallotus spodocarpys [22]), and antioxidant activities (Mallotus metcalfianus [23], Phyllanthus emblica [21], Phyllanthus niruri [25]) have been reported for both genera.…”

PHYTOCHEMICAL STUDY ON THE STEM BARK OF Mallotus leucodermis Hook F.

“…Moreover, the pharmaceutical research has found that some of chemical constituents of Mallotus have the capability to possess several biological activities such as antioxidant, anti-inflammatory, antimicrobial, antiviral, cytotoxic and antitumor activities [3]. Therefore, the outcomes from this study will improve and enhance the application of natural product in the development of drug discovery.…”

“…Mallotus is a genus of shrubs, trees and climbers with approximately 150 species were distributed in tropical and sub-tropical regions of Asia [2]. The genus of Mallotus belongs to the Malphighiales order, the Euphorbiaceae family, Acalyphoideae subfamily, Acalypeae pro parte and Rotterinae subtribe [3]. Research on Mallotus species revealed that this genus were very rich with active…”

Multivariate data analysis to evaluate the fingerprint peaks responsible for the cytotoxic activity of Mallotus species

“…The genus comprises over 140 species of which many are used as traditional medicines in Asia [20]. Over the years, the genus has provided scientists a broad basis in their research for new pharmacological compounds.…”