Mallory-Weiss Syndrome and Hypofibrinogenemia

Goodman, Julien M.

doi:10.1001/jama.1964.03070140078022

Cited by 6 publications

(1 citation statement)

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“…3 The second was an adult under anesthesia for a partial gastrectomy and vagectomy, who developed violent hiccups followed by brisk bleeding from a rent in the mucosa of the esophagogastric junction. 4 Hiccups are periodic contractions of the diaphragm and, like retching, could exert shear forces on the gastroesophageal junction and tear the mucosa. The 3 patients presented here had severe hiccups just before hematemesis; none had preceding retching or other activity typically associated with Mallory-Weiss tears, and all had hiatal hernias.…”

Section: Discussionmentioning

confidence: 99%

Hiccups: An Unappreciated Cause of the Mallory-Weiss Syndrome

Brown

2015

The American Journal of Medicine

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The Mallory-Weiss syndrome is characterized by bleeding from a mucosal tear of the gastroesophageal junction and may account for an estimated 1%-14% of all upper gastrointestinal bleeding cases. 1 Classically, the syndrome is associated with forceful vomiting or retching before the first episode of hematemesis. The mucosal tear is attributed to shearing forces on the gastroesophageal junction during high intra-abdominal pressures generated by forceful contractions of the diaphragm during vomiting, and less commonly, during severe coughing, status asthmaticus, and generalized convulsion, especially when there is a hiatal hernia. 1,2 However, some 23% of cases have no identifiable risk factor. 1 Here, I describe 3 cases of the Mallory-Weiss syndrome following bouts of severe hiccups.

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Section: Discussionmentioning

confidence: 99%