Malignes fibröses Histiozytom der Harnblasenwand nach Strahlentherapie eines Urothelkarzinoms

Nonepithelial neoplasms of the urinary bladder

“…Fibrous histiocytomas are very rare in the urinary bladder [26], whereas the storiform, fascicular, and myxoid types of malignant fibrous histiocytoma have been more frequently encountered [10,46,56]. These tumor types can develop after radio-or chemotherapy of the urinary bladder [5,16,53,57]. Immunohistochemically, positive reactions have been noted for vimentin and α-1 antichymotrypsin as well as focal positivity for CD68.…”

“…Whereas leiomyomas are more frequent in females of all ages and may account for up to 35% of all benign urinary bladder tumors [24], leiomyosarcomas are mainly found in the urinary bladder of males (70%) at an average age of 50 years. Leiomyosarcomas and malignant fibrous histiocytomas can occur as secondary tumors after irradiation of the small pelvis or after chemotherapy [53,57]. Histologically, the classical spindle cell type and the myxoid type predominate [40] (Fig.…”