Maligne Degeneration eines Morbus Gorham-Stout?

Uma causa atípica de claudicação infantil: Síndrome de Gorham-Stout com quadril fantasma

“…6 Do ponto de vista clínico, um único centro ósseo é geralmente acometido. 8 Os sítios mais comuns de SGS são a mandíbula (15%), a escápula (10%), as costelas (12%), o úmero (8%), a pelve (10 %) e o fêmur (11%). 3 O acometimento da coluna e do tórax pode provocar paraplegia e complicações respiratórias.…”

From tooth extraction to Gorham-Stout disease: A case report

“…Lala et al [14] suggested that lymphatic vessels result in the pathogenesis of GSD. Fretz et al [15] and Kulenkampff et al [16] thought that angiomatosis was responsible. Thompson and Schurman [17] suggested that the disease is a primary aberration of vascular tissue in bone related to hyperemic granulation tissue, whereas Young et al [18] believed that osteolysis is attributable to a basic underlying endothelial dysplasia of the lymphatics and/or blood vessels.…”

Gorham-Stout Syndrome: Phantom Bone Disease

“…Among these, we can cite the presence of a silent hamartoma that becomes active and starts the reabsorption after small-scale trauma. Some authors have believed that angiomatosis is responsible for the entire condition 2 , 11 . Others have described neurovascular abnormalities, like those seen in the atrophy of Sudeck (30) .…”

“…The involvement tends to be contiguous, without occurrences of multiple foci or metastases. There is one documented case of malignant degeneration that occurred in a patient with a diagnosis of hypernephroma (11) .…”