Malignant triton tumour of the parapharyngeal space

Abstract

We report the clinical course in a 25-year-old male patient of neurofibromatosis with malignant triton tumour (MTT). Triton tumour is a peripheral nerve sheath tumour with rhabdomyoblastic differentiation. This is relatively rare tumour of head and neck region and only 26 cases have been reported to date. The present case is the first reported MTT of parapharyngeal space, one of the most aggressive course among all head and neck MTTs, resulting in the death of the patient within three months following surgical resection. The aggressive nature of this tumour necessitates adjuvant therapeutic measures in addition to radical surgery in order to obtain better survival rates.

Prognostic factors for the malignant triton tumor of the head and neck

“…There are no commonly accepted guidelines for therapy. Many variations of treatment are recommended by different authors, including radical excision,10, 24 radical excision followed by postoperative irradiation and chemotherapy,11, 20, 31, 32, 40 or excision and radiotherapy 23, 29, 30, 32, 39. In particular, no local failure with radical excision and radiotherapy was noted 11.…”

Malignant triton tumor in a patient with neurofibromatosis type 1

“…In addition, the vascularity of this tumor has also been poorly described as nonhomogeneous enhancement on CT or MRI. 18,24,37 To our knowledge, CEUS fi ndings of MTT have not been previously reported. CEUS showed the outer zone to be strongly enhanced, and the internal area had very poor blood fl ow because of necrotic tissues.…”

Diagnosis and Manvagement of Common Oral and Maxillofacial Lesiovns

“…Presenting symptoms include swelling, pain, epistaxis, deviation or swelling of tonsils, nasal obstruction, and sinusitis. [16,17]…”