Malignant triton tumor of the right vagus

Bose, Amal; Deodhar, Anand; Duncan, Andrew

doi:10.1016/s0003-4975(02)03789-x

Cited by 15 publications

(9 citation statements)

References 5 publications

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“…Malignant triton tumor is named after the Triton salamander, which is able to regenerate limbs consisting of muscle, bone and nerve tissue if the cut end of the sciatic nerve is implanted into the soft tissue of its back. This regeneration was thought to be similar to the differentiation of muscular cell lines by malignant neural elements, as originally thought to occur in MTT [1,12].…”

Section: Discussionmentioning

confidence: 86%

Malignant Triton Tumor in the Abdominal Wall: A Case Report

Kitamura¹,

Abe

Baba³

et al. 2013

AMI

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Malignant triton tumor (MTT) is a rare variant of malignant peripheral nerve sheath tumor (MPNST) with rhabdomyosarcomatous differentiation. We report the case of a 54-year-old male without a history of neurofibromatosis type 1 (NF1) who had a growing abdominal wall tumor diagnosed as MTT. Computed tomography (CT), magnetic resonance imaging (MRI) and 2-[F-18]-fluoro-2-deoxy-D-glucose positron emission tomography/CT (FDG-PET/CT) were performed. The MRI and FDG-PET/CT indicated that the lateral component of the tumor was composed of many proliferative cells, corresponding to the histopathological finding of a cellular proliferation of spindle-shaped cells. In light of this case and previous reports, it is apparent that FDG-PET/CT is a helpful tool for distinguishing MTT from benign peripheral nerve sheath tumor.

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Section: Discussionmentioning

confidence: 86%

Malignant Triton Tumor in the Abdominal Wall: A Case Report

Kitamura¹,

Abe

Baba³

et al. 2013

AMI

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“…Among them, two were located in the anterior mediastinum, both of which were submitted to incomplete excision. Another case of MTT, arising from the right vagus nerve and extending from the superior mediastinum to the carinal level in a paravertebral position, has been described with no recurrence signs at 18 months postoperatively [2].…”

Section: Discussionmentioning

confidence: 98%

“…The tumour predominantly affects patients in their third and fourth decades of life, while nearly two thirds of cases are associated with von Recklinghausen's disease and concern younger patients [2,3] ence in infants and children has been reported, usually relating to genetic alterations and chromosomal aberrations [4,5]; such presence has also been reported in octogenarians [6]. Although such tumours may locate anywhere in the body, one third is located in the head and neck region [7].…”

Section: Discussionmentioning

confidence: 99%

Malignant triton tumour of the anterior mediastinum as incidental finding

Zisis

Fragoulis

Rontogianni

et al. 2016

Monaldi Arch Chest Dis

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A rare case of malignant peripheral nerve sheath tumour with rhabdomyoblastic differentiation (malignant triton tumour) of the anterior mediastinum in a 30-yearold male is reported. The tumour was an incidental finding during the diagnostic work-up following a motor vehicle accident. The patient underwent median sternotomy with a tumour resection performed. Local relapse was suspected one month later, as per the chest CT-scan, and post-operative chemoradiation was applied, which produced a response. Twelve months later the patient is doing well while radiological findings remain invariable. Localization of a triton tumour in the anterior mediastinum is extremely rare, adjuvant treatment is necessary, recurrence frequently occurs and the prognosis is dismal.

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“…The progress of the tumor happens following a prolonged latent period of 10–20 years. As per our knowledge only twelve such cases have been reported in the medical literature (Table 1) [[12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22]].…”

Section: Discussionmentioning

confidence: 99%

Mediastinal malignant triton tumor: A rare case series and review of literature

Chaudhry

Algazal

Cheema

et al. 2019

International Journal of Surgery Case Reports

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HighlightsMalignant triton tumor (MTT) is extremely rare subset of malignant peripheral nerve sheath tumor (MPNST) which accounts for < 10% of all MPNST.Due to their aggressive biological behavior prognosis is very poor.To date in medical literature only 12 cases of malignant triton tumor has been reported.We report series of three mediastinal malignant triton.Managed with radical surgical resection and neoadjuvent chemotherapy &radiotherapy.

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Malignant triton tumor of the right vagus

Cited by 15 publications

References 5 publications

Malignant Triton Tumor in the Abdominal Wall: A Case Report

Malignant Triton Tumor in the Abdominal Wall: A Case Report

Malignant triton tumour of the anterior mediastinum as incidental finding

Mediastinal malignant triton tumor: A rare case series and review of literature

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