Malignant thymoma presenting as intracardiac tumor and superior vena caval obstruction

Airan, Balram; Sharma, Raju; Iyer, Krishna; Kalia, Praveen; Singh, Mansher; Shrivastava, Savitri; Rao, I.M.

doi:10.1016/0003-4975(90)91143-y

Cited by 21 publications

(8 citation statements)

References 6 publications

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“…Local invasion occurs most commonlyinto the pleura (30%), pericardium (25%), lungs (8%), and recurrent laryngeal nerve (4%), but invasion into the intracardiac and great vessels is extremely rare (3). Only a few cases of intracardiac extension of thymomahave been reported in the English literature (3)(4)(5)(6)(7)(8)(9). Wereport a case of invasive thymomawhich extended into the right atrium and right ventricle, causing right ventricular inflow tract obstruction.…”

Section: Introductionmentioning

confidence: 99%

Successful Resection of Intracardiac Invasive Thymoma with Right Ventricular Inflow Tract Occlusion.

et al. 2000

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A 72-year-old man presenting with the superior vena cava syndromeand intracardiac mass wasadmitted to our hospital. The mass was resected and confirmed to be invasive thymoma. Three years later, he was re-admitted with recurrence into the intracardiac space without any changes in the anterior mediastinum mass. The mass occupied the right atrial cavity and protruded into the right ventricle, causing right ventricular inflow tract obstruction. He underwent re-operation and irradiation. His postoperative course was uneventful, and he has remained alive. Invasive thymomawith intracardiac extension is extremely rare.

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Section: Introductionmentioning

confidence: 99%

Successful Resection of Intracardiac Invasive Thymoma with Right Ventricular Inflow Tract Occlusion.

et al. 2000

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“…Although invasive thymoma and thymic carcinoma have a tendency to infiltrate adjacent organs in the mediastinum, almost all SVCS cases by thymomas result from the extrinsic compression by the tumor. By far, SVCS caused by the intravascular permeation with thrombus formation of malignant thymomas have been very rarely reported worldwide4,5,11, and the present case is the first report of SVCS caused by this unusual pattern of invasion in a patient with invasive thymoma in South Korea. The mechanism of this rare form of SVCS was not fully understood, but the thymic veins draining the LBCV have been suggested as possible entrance routes according to previous reports4,5.…”

Section: Discussionmentioning

confidence: 59%

“…The vast majority of SVCS cases caused by thymomas are developed by the extrinsic compression of the superior vena cava (SVC) rather than the direct vascular invasion of the tumor. In addition, although invasive thymoma and thymic carcinoma have a tendency to infiltrate adjacent organs, such as the mediastinal pleura, lungs, pericardium, great vessels and heart4, there are very few reports in the medical literature regarding SVCS caused by an invasive thymoma protruding into the left brachiocephalic vein (LBCV) and SVC with thrombus formation5,6.…”

Section: Introductionmentioning

confidence: 99%

An Unusual Case of Superior Vena Cava Syndrome Caused by the Intravascular Invasion of an Invasive Thymoma

Kim

Cho

et al. 2013

Tuberc Respir Dis

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Superior vena cava syndrome (SVCS) is usually caused by extrinsic compression or invasion of the superior vena cava (SVC) by malignant tumors involving mediastinal structures. Although thymomas are well-known causes of SVCS, cases of SVCS caused by malignant thymomas protruding into adjacent vessels draining the SVC with thrombosis have been very rarely reported worldwide. We experienced a 39-year-old female patient with SVCS that developed after the direct invasion of the left brachiocephalic vein (LBCV) and SVC by an anterior mediastinal mass with a high maximum standardized uptake value on the chest computed tomography (CT) and positron emission tomography-CT. Based on these results, she underwent en bloc resection of the tumor, including removal of the involved vessels, and was eventually diagnosed as having a type B2 thymoma permeating into the LBCV and SVC. We present this case as a very rare form of SVCS caused by an invasive thymoma.

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“…Invasive thymoma is characterized by infiltration and extension into the neighboring structures, and metastasis is usually confined to the pleura, pericardium, or diaphragm . The intraluminal extension of the thymoma with thrombus formation through LBCV, RBCV and SVC into the right atrium is uncommon.…”

Section: Discussionmentioning

confidence: 99%

Invasive thymoma with intravascular growth into the great veins and right atrium: A case report

et al. 2020

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Here, we present a case of invasive thymoma with intraluminal growth into the left and right brachiocephalic veins, superior vena cava and the right atrium. Resection of the mass, double partial upper lobe lobectomy and superior vena cava, and left and right brachiocephalic vein replacement were performed. Pathological diagnosis indicated a mixed histological pattern indicative of type B1 and type B2 thymoma, predominantly type B2 thymoma. The patient was well and without local recurrence or distal metastasis after 50 months of follow-up.

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Malignant thymoma presenting as intracardiac tumor and superior vena caval obstruction

Cited by 21 publications

References 6 publications

Successful Resection of Intracardiac Invasive Thymoma with Right Ventricular Inflow Tract Occlusion.

Successful Resection of Intracardiac Invasive Thymoma with Right Ventricular Inflow Tract Occlusion.

An Unusual Case of Superior Vena Cava Syndrome Caused by the Intravascular Invasion of an Invasive Thymoma

Invasive thymoma with intravascular growth into the great veins and right atrium: A case report

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