Malignant struma ovarii: Report of two cases and selected review of the literature

Zakhem, Antoine; Aftimos, George; Kreidy, Raghid; Salem, Philip A.

doi:10.1002/jso.2930430116

Cited by 48 publications

(21 citation statements)

References 12 publications

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“…Malignant struma ovarii is a very rare disease [9][10][11][12]. The clinical course of extraovarian spread and the gold standard therapy have not been fully established.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii

Seo

Ryu

Lee

et al. 2014

Nucl Med Mol Imaging

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“…Malignant struma ovarii is a very rare disease [9][10][11][12]. The clinical course of extraovarian spread and the gold standard therapy have not been fully established.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii

Seo

Ryu

Lee

et al. 2014

Nucl Med Mol Imaging

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“…In addition, this tumor can, eventually, be associated GD (214,215) (D,C). Differential diagnosis with other causes of hyperthyroidism is based on the low radioactive iodine uptake and the presence of an ovarian tumor on imaging studies (213,215). Treatment consists in the surgical removal of the tumor after achieving euthyroidism through ATD treatment.…”

Section: How Should Thyrotoxicosis Due To Struma Ovarii Be Assessementioning

confidence: 99%

Consenso brasileiro para o diagnóstico e tratamento do hipertireoidismo: recomendações do Departamento de Tireoide da Sociedade Brasileira de Endocrinologia e Metabologia

Maia

Scheffel

Meyer

et al. 2013

Arq Bras Endocrinol Metab

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SIntroduction: Hyperthyroidism is characterized by increased synthesis and release of thyroid hormones by the thyroid gland. Thyrotoxicosis refers to the clinical syndrome resulting from excessive circulating thyroid hormones, secondary to hyperthyroidism or due to other causes. This article describes evidence-based guidelines for the clinical management of thyrotoxicosis. Objective: This consensus, developed by Brazilian experts and sponsored by the Department of Thyroid Brazilian Society of Endocrinology and Metabolism, aims to address the management, diagnosis and treatment of patients with thyrotoxicosis, according to the most recent evidence from the literature and appropriate for the clinical reality of Brazil. Materials and methods: After structuring clinical questions, search for evidence was made available in the literature, initially in the database Medline, PubMed and Embase databases and subsequently in SciELO -Lilacs. The strength of evidence was evaluated by Oxford classification system was established from the study design used, considering the best available evidence for each question. Results: We have defined 13 questions about the initial clinical approach for the diagnosis and treatment that resulted in 53 recommendations, including the etiology, treatment with antithyroid drugs, radioactive iodine and surgery. We also addressed hyperthyroidism in children, teenagers or pregnant patients, and management of hyperthyroidism in patients with Graves' ophthalmopathy and various other causes of thyrotoxicosis. Conclusions: The clinical diagnosis of hyperthyroidism usually offers no difficulty and should be made with measurements of serum TSH and thyroid hormones. The treatment can be performed with antithyroid drugs, surgery or administration of radioactive iodine according to the etiology of thyrotoxicosis, local availability of methods and preferences of the attending physician and patient. Arq Bras Endocrinol

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“…Among the 8 patients with adequate follow-up no deaths were seen at a median follow-up of 7.3 years. However, cases of metastatic disease have been noted at presentation or on follow-up [2,5,6,8,9,11,12,[15][16][17][18]. Radioactive iodine was utilized to treat 7 of these patients [2,8,11,12,15,18].…”

Section: Discussionmentioning

confidence: 99%

Malignant Struma ovarii: Report of a Case and Review of the Literature

Kostoglou-Athanassiou

Lekka-Katsouli²,

Gogou³

et al. 2002

Horm Res Paediatr

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Malignant struma ovarii is a very rare disease and therefore there is neither common agreement on treatment regimens nor sufficient follow-up experience. The case of a 38-year-old woman with malignant struma ovarii is described. The patient presented with a clinically silent ovarian neoplasm discovered incidentally during investigations for metrorrhagia. The ovarian mass was resected and the tumor was found to be a teratoma. Within the teratoma a papillary thyroid carcinoma of the follicular variant was found. Subsequently, in order to make follow-up of the patient possible by thyroglobulin measurement and radioiodine whole body scintigraphy, near-total thyroidectomy was performed and the thyroid was found to be normal on histology. Whole body radioiodine scintigraphy with ¹³¹I and ablation of the thyroid remnant by the administration of 80 mCi ¹³¹I was performed. The patient recovered uneventfully and is now well.

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Malignant struma ovarii: Report of two cases and selected review of the literature

Cited by 48 publications

References 12 publications

Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii

Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii

Consenso brasileiro para o diagnóstico e tratamento do hipertireoidismo: recomendações do Departamento de Tireoide da Sociedade Brasileira de Endocrinologia e Metabologia

Malignant Struma ovarii: Report of a Case and Review of the Literature

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