Malignant solitary fibrous tumor in retroperitoneum

Zhou, Yihong; Chen, Xi; Ye, Yi; Tong, Liang; Dai, Yingbo

doi:10.1097/md.0000000000006373

Cited by 16 publications

(17 citation statements)

References 23 publications

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“…SFTs were originally thought to only arise in the thoracic cavity, but it is now known that while most SFTs are intrathoracic and usually from the pleura, these tumors are frequently found in various locations throughout the body [6,7]. Peritoneal cavities, usually the retroperitoneum or pelvic soft tissue, are the primary site of origin in 30% of SFTs [8,9]. 20% occur in Case Reports in Medicine the head and neck, the meninges, or extracranial locations [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

Kaya

Carlson

Thomas

et al. 2020

Case Reports in Medicine

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We present a unique case of a patient simultaneously diagnosed with solitary fibrous tumor (SFT) and unrelated adenocarcinoma of the lung, both proven with separate pathology. It was subsequently found that the SFT had metastasized to the brain by additional pathology, and not the predicted adenocarcinoma. SFTs are a rare mesenchymal neoplasm that accounts for less than 2% of all reported soft tissue tumors. SFTs most commonly arise in the thoracic cavity, but are frequently found in various locations throughout the body, and rarely metastasize to the brain. This case highlights that rare neoplasms, such as SFT, should not be ruled out as a potential cause of metastasis. Due to the rarity of this clinical situation, we also provide a review and discussion of previously reported SFT cases and the use of postoperative radiation therapy. The optimal treatment for individual patients remains unclear in this unique situation. Surgical resection followed by adjuvant Gamma Knife radiation therapy to the surgical bed appears to be a safe option for local treatment of SFT in select patients. Further studies are needed of this rare clinical situation in order to better understand and optimize future treatments for patients with SFT and metastasis to the brain.

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Section: Discussionmentioning

confidence: 99%

Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

Kaya

Carlson

Thomas

et al. 2020

Case Reports in Medicine

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“…These tumors arise in a wide range of anatomic sites. Approximately 30% from thoracic cavity, most commonly from pleura [2] , [3] , and 30% from peritoneal cavity, most commonly from retroperitoneum and pelvic soft tissues [4] , [5] , [6] . About 20% occur in head and neck [7] , [8] , the meninges [9] , or extracranial sites such as the sinonasal tract [10] , oral cavity [11] , deep tissue of the neck, and the orbit [12] .…”

Section: Discussionmentioning

confidence: 99%

Solitary fibrous tumor of the abdominal wall re-surfacing as unilateral pleural effusion and mass: A case report and review of the literature

Zhai

Chun

2018

Respiratory Medicine Case Reports

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BackgroundSolitary fibrous tumors (SFTs) are rare fibroblastic mesenchymal neoplasms that were initially described in the pleura, but have been increasingly recognized to occur in other parts of the body. They have been traditionally regarded as indolent tumors that are rare to metastasize after surgical resection. Here, we describe a case of a Filipino female who initially presented with unilateral pleural effusion and mass, and was ultimately diagnosed with recurrent solitary fibrous tumor that originated from the abdominal wall. Then, we reviewed existing literature on intra- and extrathoracic SFTs with focus on pathological characteristics, recommendations for treatment as well as post-treatment surveillance.Case presentationA 79-year-old Filipino female with a history of solitary fibrous tumor of the abdominal wall status post complete surgical resection 3 years ago presented with unilateral pleural effusion and mass, and was diagnosed with recurrent solitary fibrous tumor that metastasized to the lung. She was not a candidate for systemic chemotherapy and ultimately died 1 year later from progressive respiratory failure.ConclusionsSolitary fibrous tumor are rare mesenchymal tumors that were initially described in the pleura, but have now been reported in many other sites. Complete surgical resection is the mainstay therapy for all cases; however, long-term monitoring and surveillance several years after initial presentation is crucial to prevent disease recurrence, and adjuvant treatment may be necessary for patients with high-risk features. Additional studies are needed to demonstrate the clinical utility of risk stratification models and to develop post-treatment surveillance guidelines for extrathoracic SFTs.

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“…Extrapleural lesions are more common than pleural lesions. Around 30–40% of extrapleural SFTs arise in deep soft tissues, including the abdominal cavity, pelvis, and retroperitoneum [ 83 , 84 ]. SFTs most commonly affect adults, with a peak incidence between 40 and 70 years.…”

Section: Rare Retroperitoneal Sarcomasmentioning

confidence: 99%

Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach

Choi

2020

Diagnostics

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Retroperitoneal sarcomas are a heterogenous group of rare tumors arising in the retroperitoneum. Retroperitoneal sarcomas comprise approximately 10% of all soft tissue sarcomas. Though any soft tissue sarcoma histologic types may arise in the retroperitoneal space, liposarcoma (especially well-differentiated and dedifferentiated types) and leiomyosarcoma do so most commonly. Retroperitoneal sarcomas are diagnostically challenging, owing to their diversity and morphological overlap with other tumors arising in the retroperitoneum. An accurate diagnosis is necessary for correct management and prognostication. Herein, we provide an update on the diagnostic approach to retroperitoneal sarcomas and review their key histologic findings and differential diagnoses.

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Malignant solitary fibrous tumor in retroperitoneum

Cited by 16 publications

References 23 publications

Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

Solitary fibrous tumor of the abdominal wall re-surfacing as unilateral pleural effusion and mass: A case report and review of the literature

Retroperitoneal Sarcomas: An Update on the Diagnostic Pathology Approach

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