Malignant Schwannoma of the Sciatic Nerve Originating in a Spinal Plexiform Neurofibroma Associated With Neurofibromatosis Type 1. Case Report.

Topsakal, Cahide; Akdemir, Ismail; Tiftikci, Murat; Özercan, İbrahim; Aydın, Yunus

doi:10.2176/nmc.41.551

Cited by 30 publications

(18 citation statements)

References 31 publications

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“…Common nerve mass lesions are peripheral nerve sheath tumors (schwannoma and neurofibroma) and lesions that can be associated with neurocutaneous syndromes (neurofibromatosis, schwannomatosis; NF, SW). These have been well described in the literature [18][19][20][21][22][23][24][25][26][27]. The authors review other uncommon tumor and tumor-like lesions and describe their pertinent imaging features on high-resolution MR imaging.…”

Section: Sciatic Nerve-normal Anatomy and Imaging Appearancementioning

confidence: 99%

Sciatic nerve tumor and tumor-like lesions—uncommon pathologies

et al. 2012

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Section: Sciatic Nerve-normal Anatomy and Imaging Appearancementioning

confidence: 99%

Sciatic nerve tumor and tumor-like lesions—uncommon pathologies

et al. 2012

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“…2,10,12,16 Surgical excision is the treatment of choice. Schwannomas are theoretically removable since they repulse fascicular groups without penetrating them thus allowing their enucleation while preserving nerve continuity, 8,11,14,15 as reported in our patient. Microsurgical excision should be performed using electrical stimulation to facilitate detection of motor fascicles.…”

Section: Discussionmentioning

confidence: 54%

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

ElEmam

Hasan

Elsebaey

2018

Egyptian Spine Journal

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Background Data: Schwannomas originating from the sciatic nerve are extremely rare and usually present as a pathological mass on palpable examination or pain located in the thigh. Motor and sensory deficits are observed more often with big size lesions. Purpose: To describe a rare case of giant schwannoma of the sciatic nerve with 2 years delay in management. Study Design: Case report and review of the literature. Patients and Methods: A 19-years-old female patient was referred to Suez Canal University Hospital after 6 years of pain and 2 years of improper management. She presented with increasing swelling in the posterior aspect of her right thigh associated with paresthesia and weakness. After neurological examination an MRI of the right thigh was done and revealed huge mass attached to the right sciatic nerve. Results: Surgical excision was undertaken, carefully dissecting the lesion from the sciatic nerve. Histopathological examination revealed a sciatic nerve schwannoma. The patient had marked postoperative recovery with marked pain reduction and improved neurological deficits. Conclusion: Schwannomas of the sciatic nerve are eccentrically located on the nerve. they should be systematically suspected if thigh mass or persistent sciatica is reported. Surgical excision has good prognosis. (2018ESJ157)

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“…They generally appear as solitary lesions. Occurrence of multiple schwannomas is rare and not necessarily correlate with neurofibromatosis, which demonstrates very precise chromosomal alterations 8. Malignant transformation of benign schwannomas is unusual 9.…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Median Nerve: Diagnosis Sometimes Delayed

Boufettal

Azouz

Rhanim

et al. 2014

Clin Med Insights Case Rep

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Schwannoma is a tumor that develops from nerve sheath. The authors report an unusual case of schwannoma of the median nerve (MN) that remained asymptomatic for four years. The diagnosis was based on MRI (magnetic resonance imaging) and histopathological examination. Surgical removal is usually curative. The asymptomatic character of the tumor and its slow evolution remain an essential factor in diagnosis delays. This tumor has a good prognosis with a low recurrence rate and potential for malignant transformation.

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Malignant Schwannoma of the Sciatic Nerve Originating in a Spinal Plexiform Neurofibroma Associated With Neurofibromatosis Type 1. Case Report.

Cited by 30 publications

References 31 publications

Sciatic nerve tumor and tumor-like lesions—uncommon pathologies

Sciatic nerve tumor and tumor-like lesions—uncommon pathologies

Neglected Giant Schwannoma of the Sciatic Nerve. Case Report and Literature Review

Schwannoma of the Median Nerve: Diagnosis Sometimes Delayed

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