Malignant schwannoma of the intrathoracic vagus nerve: Report of a case

Maebeya, Shinji; Miyoshi, Shinichiro; Fujiwara, Keiichi; Sekii, Hiroyosi; Suzuma, Takaomi; Yosimasu, Tatuya; Naito, Yasuaki; Nishino, Eisei

doi:10.1007/bf00309097

Cited by 15 publications

(11 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…10,11 It may be possible to preserve the nerve during excision of schwannoma, because schwannomas are encapsulated lesions of nerve sheath origin, which grow from the formation of a lateral mass on the parent nerve, often making the nerve easily identifiable. Conversely, neurofibromas are non-encapsulated, they possess a poorly organized structure, and they grow by diffusely expanding the parent nerve containing all nerve elements, including axons, sheath cells, and connective tissue, which may prevent the axons from being identified as they course through the tumor.…”

Section: Discussionmentioning

confidence: 99%

Mediastinal Neurofibroma Originating from the Left Intrathoracic Phrenic Nerve: Report of a Case

et al. 2004

View full text Add to dashboard Cite

We report a case of mediastinal neurofibroma originating from the left phrenic nerve in a 42-year-old woman who was referred to us after a routine chest X-ray showed a smooth, round abnormal shadow in the left middle lung field adjacent to the heart. We resected a 25 x 20 x 20-mm tumor by video-assisted thoracic surgery. Histopathological examination confirmed that the lesion was a mediastinal neurofibroma originating from the left phrenic nerve without von Recklinghausen's disease. Neurogenic mediastinal tumors originating from the phrenic nerve are very rare, and to the best of our knowledge, no other case of a mediastinal neurofibroma originating from the phrenic nerve in a patient without von Recklinghausen's disease has ever been reported.

show abstract

Section: Discussionmentioning

confidence: 99%

Mediastinal Neurofibroma Originating from the Left Intrathoracic Phrenic Nerve: Report of a Case

et al. 2004

View full text Add to dashboard Cite

show abstract

“…Tumors of vagus nerve origin are observed in about 2% of all neurogenic tumors of the mediastinum [ 4 ], however, no instace of malignant schwannoma was reported in this review. To our knowledge, only a few such cases have been previously reported [ 5 - 7 ]. As a result, malignant schwannoma originating from the vagus nerve is therefore considered to be extremely rare.…”

Section: Discussionmentioning

confidence: 99%

Malignant schwannoma of the upper mediastinum originating from the vagus nerve

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Berdasarkan lokasi massa, pasien kemungkinan merasakan gejala terkait iritasi dan atau defisit terkait kompresi atau infiltratif dari plexsus brachialis dan ganglion cervical yaitu berupa batuk dan nyeri dada. 7,10 Nyeri dada, disfagia dan sesak dapat disebabkan gejala lokal tumor yaitu akibat sekunder dari invasi tumor sehingga ukuran tumor sudah menyebabkan distorsi anatomis dari mediastinum. Sesak napas dapat juga disebabkan karena adanya efusi pleura masif yang merupakan akibat adanya infiltratif tumor.…”

Section: Tanda Dan Gejala Mpnstunclassified

Seorang Laki-Laki dengan Tumor Mediastinum Posterior ( Malignant Peripheral Nerve Sheath Tumor )

Maranatha

Yuniati

2019

View full text Add to dashboard Cite

Background: Malignant tumors arising from peripheral nerves or displaying differentiation along the lines of the various elements of the nerve sheath are referred to Malignant peripheral nerve sheath tumors (MPNST) and also called malignant schwannomas or neurofibrosarcomas. The common sites of involvement are head, neck, extremities and thorax. This case was discussed due to its rare incidence, namely less than 5% of soft tissue malignant tumor. The overall five year survival rate is approximately 50% in patients with resectable tumor. Case: We report a case of MPNST arising from mediastinum, the patient was a male, 41-years-old, with chief complaint are chest pain and mass in the back. Contrast enhanced chest CT Scan showed a solid mass (10.02 × 6.97 × 10.53 cm) in the right side of the posterior mediastinum. On microscopic examination with hematoxylin eosin imunostaining, of the mass on mediastinum showed typical features of MPNST, which were positive for S-100 imunostaining. Based on convensional histopathologic and imunostaining, this case was concluded as Malignant peripheral nerve sheath tumors (MPNST). Conclusion: The treatment of chest wall MPNSTs is multimodality, including wide local excision, adjuvant radiotherapy, and chemotherapy. In our case, we performed direct excision due to the infiltrating mass to the surrounding tissue, so the prognosis for this case was good. This case indicates the role of chemotherapy in treatment of advanced MPNST. Studies shows the superiority of the doxorubicin–ifosfamide regimen. As in this case the patient showed complete respons after surgery and adjuvant chemotherapy.

show abstract

Malignant schwannoma of the intrathoracic vagus nerve: Report of a case

Cited by 15 publications

References 4 publications

Mediastinal Neurofibroma Originating from the Left Intrathoracic Phrenic Nerve: Report of a Case

Mediastinal Neurofibroma Originating from the Left Intrathoracic Phrenic Nerve: Report of a Case

Malignant schwannoma of the upper mediastinum originating from the vagus nerve

Seorang Laki-Laki dengan Tumor Mediastinum Posterior ( Malignant Peripheral Nerve Sheath Tumor )

Contact Info

Product

Resources

About