Malignant Peritoneal Mesothelioma With Butterfly-Shaped Muscle Metastasis

Abstract

Malignant peritoneal mesothelioma is a rare malignancy that may manifest as extraperitoneal metastasis. We describe the findings of 68 Ga-FAPI and 18 F-FDG PET/CT in a case of malignant peritoneal mesothelioma with widespread muscle metastasis in a butterfly-shaped distribution pattern. We found that FDG and FAPI uptake in the peritoneal tumor and its spread were inhomogeneous. Notably, 68 Ga-FAPI PET/CT more clearly showed relevant lesions compared with 18 F-FDG PET/CT.

Malignant Peritoneal Mesothelioma Complicating Familial Mediterranean Fever on 18F-FDG PET/CT

“…This imaging modality may therefore be useful for the early detection of this potentially life-threatening peritoneal complication of FMF in selected patients. Finally, although we did not perform a 68 Ga-FAPI PET/CT in this patient, it has recently been suggested that this could be of interest in disseminated forms of MPM 9 and could therefore be a valuable tool in case of dubious 18 F-FDG PET/CT.…”

18F-FDG and 68Ga-PSMA PET/CT in Paratesticular Mesothelioma

“…Ga-PSMA-positive (partly mild 18 F-FDG-avid) skeletal metastases from prostate cancer verified by histopathology as prostatic adenocarcinoma with small cell neuroendocrine differentiation. [4][5][6][7][8]…”

“… 18 F-FDG PET/CT MIP ( A ) and transaxial PET (top), fusion PET/CT (mid), and CT (low) images ( B ) showed focal increased tracer uptake in the left scrotal region consistent with local recurrence confirmed by histopathology as epithelioid mesothelioma ( A and B , arrowheads) with multiple 18 F-FDG–avid lesions in the left pleura suggestive of malignant mesothelioma ( A , arrows). 68 Ga-PSMA PET/CT MIP ( C ) and transaxial PET (top), fusion PET/CT (mid), and CT (low) images ( D ) revealed disseminated 1–4 68 Ga-PSMA–positive (partly mild 18 F-FDG–avid) skeletal metastases from prostate cancer verified by histopathology as prostatic adenocarcinoma with small cell neuroendocrine differentiation 4–8 …”