Malignant peripheral nerve sheath tumor of the cauda equina with craniospinal metastasis

Thomas, Jonathan G.; Lincoln, Christie M.; Goodman, J. Clay; Gopinath, Shankar P.

doi:10.1016/j.jocn.2014.02.028

Cited by 9 publications

(19 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As found in our patient, the spinal MPNST lesions were described as non-homogenous hyperintense in T2WI and isointense in T1WI that enhanced after gadolinium injection (15,21). The hyperintense area on T2WI was reported as a central cystic lesion or necrosis (4).…”

Section: █ Discussionsupporting

confidence: 72%

“…We summarized them in Table I. They are primarily distributed in: cervical in 7 patients (30%) (2,8,17,23), thoracic and thoracolumbar in 6 (26%) (7,15,17,23), and lumbar in 10 (44%) (1,3,7,14,17,21,22,24,25). Our patient had an intradural extramedullary cervical tumor extending from foramen magnum to lower cervical vertebrae with severely invasion of the spinal cord.…”

Section: █ Discussionmentioning

confidence: 93%

“…The hyperintense area on T2WI was reported as a central cystic lesion or necrosis (4). The leptomeningeal metastasis was hypointense in T2WI and enhanced homogenously (14,15,21,24). The spinal seeding is defined as a "string-of-beads" pattern since they are small enhancing lesions spreading along the spinal cord (15).…”

Section: █ Discussionmentioning

confidence: 99%

“…The spinal seeding is defined as a "string-of-beads" pattern since they are small enhancing lesions spreading along the spinal cord (15). MRI may reveal leptomeningeal thickening and enhancement (21).…”

Section: █ Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Spinal intradural primary malignant peripheral nerve sheath tumor with leptomeningeal seeding: case report and literature review

Baharvahdat¹,

Ganjeifar²,

Roshan³

et al. 2016

Turkish Neurosurgery

View full text Add to dashboard Cite

Spinal intradural primary malignant peripheral nerve sheath tumors (MPNST) are rare in patients without neurofibromatosis. Here we represent a 3-year-old girl of primary intradural spinal malignant peripheral nerve sheath tumor. The tumor was removed partially and MPNST was diagnosed in the histopathological examination. Her condition deteriorated due to acute hydrocephalus in the following days. In this article, we discuss the clinical presentation, imaging, treatment, and prognosis of our patient and the other 22 patients of primary intradural MPNST, found in the literature. The Kaplan?Meier method was applied for univariate analysis and Cox proportional hazards model for multivariate analysis. This analysis showed that age, was an important factor predicting short-term survival of patients with MPNST.

show abstract

Section: █ Discussionsupporting

confidence: 72%

Section: █ Discussionmentioning

confidence: 93%

Section: █ Discussionmentioning

confidence: 99%

Section: █ Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Spinal intradural primary malignant peripheral nerve sheath tumor with leptomeningeal seeding: case report and literature review

Baharvahdat¹,

Ganjeifar²,

Roshan³

et al. 2016

Turkish Neurosurgery

View full text Add to dashboard Cite

show abstract

“…Unique to this case, however, is the rapid development of disseminated disease two weeks a er surgery. Patients in other reported cases of intradural MPNSTs with leptomeningeal spread were diagnosed with dissemination ranging from present on presentation to 24 months following initial surgery [10][11][12][13][14][15][16][17][18][19]. e authors advocate that regardless of imaging characteristics or the duration since radiation, surgeons should retain a high index of suspicion for a MPSNT.…”

Section: Operative Coursementioning

confidence: 99%

Ominous Occurrence of Spinal Intradural Primary Malignant Peripheral Nerve Sheath Tumor Four Decades following Radiation Therapy for Testicular Seminoma

Shammassian

Chugh

et al. 2020

Case Reports in Neurological Medicine

View full text Add to dashboard Cite

Primary intradural malignant peripheral nerve sheath tumor (MPNST) is an extremely rare diagnosis and is associated with an extremely poor prognosis. A 77-year-old man diagnosed with an intradural MPNST, more than 40 years after radiation for a testicular seminoma, is reported. Intradural MPNSTs of the spine outside the setting of neurofibromatosis is extremely rare and can masquerade as common benign nerve sheath tumors, on imaging. An older age at presentation with short duration of symptoms and prior regional radiation treatment encompassing the spine in the treatment field regardless of remoteness should alert the oncologists and neurosurgeons to the possible existence of this rare and aggressive tumor, as the management, and overall prognosis of this tumor is distinctly different compared to the usual intradural spinal tumors.

show abstract

Cauda equina thickening: an approach to MRI findings

et al. 2023

View full text Add to dashboard Cite

Malignant peripheral nerve sheath tumor of the cauda equina with craniospinal metastasis

Cited by 9 publications

References 5 publications

Spinal intradural primary malignant peripheral nerve sheath tumor with leptomeningeal seeding: case report and literature review

Spinal intradural primary malignant peripheral nerve sheath tumor with leptomeningeal seeding: case report and literature review

Ominous Occurrence of Spinal Intradural Primary Malignant Peripheral Nerve Sheath Tumor Four Decades following Radiation Therapy for Testicular Seminoma

Cauda equina thickening: an approach to MRI findings

Contact Info

Product

Resources

About