Malignant pancreatic tumors: incidence and outcome in 58 pediatric patients

Pérez, Eduardo A.; Gutierrez, Juan C.; Koniaris, Leonidas G.; Neville, Holly L.; Thompson, William R.; Sola, Juan E.

doi:10.1016/j.jpedsurg.2008.10.039

Cited by 122 publications

(130 citation statements)

References 32 publications

(42 reference statements)

Supporting

Mentioning

122

Contrasting

Unclassified

Order By: Relevance

“…The prognosis of pancreatic tumors in children after surgical resection is highly variable and may depend on the tumor’s nature and surgical margins [1,3,4,7,22]. Overall, the most frequent histotypes (SPT, PB, acinar cell carcinomas and NET) show long-term survival rates, although the risk of recurrence in PB seems to be high [4,12].…”

Section: Discussionmentioning

confidence: 99%

Surgical Treatment of Pancreatic Tumors in Childhood and Adolescence: Uncommon Neoplasms with Favorable Outcome

Marchegiani¹,

Crippa

Malleo³

et al. 2011

Pancreatology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Surgical Treatment of Pancreatic Tumors in Childhood and Adolescence: Uncommon Neoplasms with Favorable Outcome

Marchegiani¹,

Crippa

Malleo³

et al. 2011

Pancreatology

View full text Add to dashboard Cite

“…Independent factors of improved survival are female sex and surgical treatment. 53 The most common primary pancreatic neoplasms are pan creatoblastoma, solid pseudopapillary neoplasm of the pan creas, and pancreatic endocrine neoplasms/islet cell tumors. Complete surgical resection is the best treatment for primary pancreatic neoplasms.…”

Section: Pediatric Pancreatic Surgerymentioning

confidence: 99%

Whipple procedure: patient selection and special considerations

Tan-Tam¹,

Segedi²,

Chung³

2016

OAS

View full text Add to dashboard Cite

At the inception of pancreatic surgery by Dr Whipple in 1930s, the mortality and morbidity risk was more than 20%. With further understanding of disease processes and improve ments in pancreas resection techniques, the mortality risk has decreased to less than 5%. Age and chronic illnesses are no longer a contraindication to surgical treatment. Life expectancy and quality of life at a later age have improved, making older patients more likely to receive pancreatic surgery, thereby also putting emphasis on operative patient selection to minimize complica tions. This review summarizes the benign and malignant illnesses that are treated with pancreas operations, and innovations and improvements in pancreatic surgery and perioperative care, and describes the careful selection process for patients who would benefit from an operation. These indications are not reserved only to Whipple operation, but to pancreatectomies as well.

show abstract

“…Pancreatic malignancies are distinctly rare in childhood with an overall incidence of 0.018 cases per 100,000 children [ 28 ]. There were 58 cases of malignant pancreatic neoplasms in patients under 20 years of age reported to the SEER registry between 1973 and 2004 [ 28 ].…”

Section: Pancreasmentioning

confidence: 99%

“…There were 58 cases of malignant pancreatic neoplasms in patients under 20 years of age reported to the SEER registry between 1973 and 2004 [ 28 ]. These consisted of 31 exocrine tumors (ten solid pseudopapillary neoplasm, ten pancreatoblastomas, seven ductal adenocarcinomas, and four acinar cell carcinomas), 19 NETs, and 5 sarcomas.…”

Section: Pancreasmentioning

confidence: 99%

See 1 more Smart Citation

Gastrointestinal, Pancreatic and Hepatic Malignancies in Children

Towbin

Rowland

Parham

2014

Pediatric Malignancies: Pathology and Imaging

View full text Add to dashboard Cite

The gastrointestinal tract, liver, and pancreas are uncommon sites for primary malignant neoplasms in the pediatric population. None of the individual malignant neoplasms of these sites represented more than 2 % of cancer diagnoses in children between 0 and 19 years of age in the SEER database [ 1 ]. This is in marked contrast to the frequency of malignant neoplasms of these sites in adulthood. Gastrointestinal TractLymphoma is the most common pediatric gastrointestinal tract malignancy, accounting for approximately 75 % of malignancies in most series. This is followed by neuroendocrine tumors (NET), adenocarcinoma, and sarcoma [ 2 -4 ]. Carcinomas and a variety of rare neoplasms can occur in the gastrointestinal tract but are not addressed in this chapter. Lymphoma is discussed in another chapter.

show abstract

Malignant pancreatic tumors: incidence and outcome in 58 pediatric patients

Cited by 122 publications

References 32 publications

Surgical Treatment of Pancreatic Tumors in Childhood and Adolescence: Uncommon Neoplasms with Favorable Outcome

Surgical Treatment of Pancreatic Tumors in Childhood and Adolescence: Uncommon Neoplasms with Favorable Outcome

Whipple procedure: patient selection and special considerations

Gastrointestinal, Pancreatic and Hepatic Malignancies in Children

Contact Info

Product

Resources

About