Malignant otitis externa in an infant with selective IgA deficiency: a case report

Malignant otitis externa hospitalizations: Analysis of patient characteristics

“…It has been suggested that, although there is very low-to-absent risk of mortality, pediatric MOE patients tend to appear more ill upon presentation. 2,7,20 Our analysis seems to support this view because a greater proportion of pediatric patients were admitted nonelectively, but the cohort experienced no cases of in-hospital mortality. Interestingly, the pediatric cohort seemed to fare significantly better than the adult/elderly cohort with regard to most outcome measures studied, including length of stay and total hospital charges.…”

Malignant Otitis Externa

“…Although rare, MOE has been reported in children who have diabetes and other immunocompromised states, including IgG subclass deficiency [12], IgA deficiency [13], acute monocytic leukemia [14], iatrogenic neutropenia secondary to induction chemotherapy for acute lymphoblastic leukemia [15], and bone marrow transplantation [16]. Compared with adults, diabetes is not as common a comorbidity in children (21% in one review [14]) as are other immunocompromised states.…”

Management of malignant (necrotising) otitis externa

“…Fluoroquinolones are used cautiously in children because of the problems (identified in animals) related to joint development; 47 however, reviews highlight ciprofloxacin as being safe in selected cases 48 . Successful treatment of children with ciprofloxacin has been reported following failure of penicillin and aminoglycoside therapy 49 . Paediatric cases are usually treated with intravenous cephalosporins 50…”