Malignant middle cerebral artery infarct: A clinical case report

Abstract

Background: Ischaemic stroke accounts for 87% of strokes and occurs when a clot or a thrombus blocks a blood vessel, cutting off blood flow to a part of the brain. If large areas of brain are affected, spaceoccupying oedema may result, leading to rapid neurological deterioration, coma and death. Malignant middle cerebral artery infarction (MMCAI) is a life-threating ischaemic stroke involving the whole middle cerebral artery (MCA) territory and comprises up to 10% of MCA infarctions. Methods: We report the case of a 62 year old female 'Mary' who presented with a MMCAI together with a summary of the most recent and relevant evidence for treatment options in terms of survival and quality of life for her. We also focus on the vital role of the nurse in Mary's care and treatment. Results: Intravenous thrombolysis and endovascular clot retrieval (ECR) during the hyperacute phase have been shown to improve outcomes but Mary did not meet the criteria for thrombolysis and received unsuccessful ECR. Her neurological condition deteriorated so she underwent surgical decompression, which is one of the major advances for MMCAI treatment together with expert neuro critical care nursing. Mary made a good functional recovery, returning home to live independently. Conclusion: This case highlights the need to consider all contextual and patient preferences in relation to treatment options. In addition the case emphases the vital role the neuro critical care nurse specialist plays in the complex assessment and treatment of this patient who experienced a MMCAI and underwent complex interventions.

Meta-Analysis of Predictive Role of Early Neurological Deterioration after Intravenous Thrombolysis

“…rombolytics are injected through the distal end of the catheter, which is typically pumped into a vein. It sprays thrombolytic drugs onto the thrombus through such side holes, resulting in direct thrombolysis [9]. e thrombolytic efficiency of direct contact thrombolysis is higher, and the effect of thrombolysis is better.…”