Malignant mesothelioma of tunica vaginalis: an extremely rare case presenting without risk factors

Akın, Yiğit; Başsorgun, İbrahim; Başara, Işıl; Yücel, Selçuk

doi:10.11622/smedj.2015053

Cited by 30 publications

(23 citation statements)

References 14 publications

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“…As the disease was localized in the present case, radical inguinal orchiectomy was performed, without retroperitoneal lymphadenectomy. It has been reported that, if any sign of metastasis is evident in the inguinal lymph nodes, inguinal lymph node dissection is required (20). The usefulness of adjuvant chemotherapy and/or radiotherapy has not been clearly demonstrated due to the limited number of reported cases.…”

Section: Discussionmentioning

confidence: 99%

Malignant mesothelioma of the tunica vaginalis testis: A case report and literature review

Zhang

et al. 2017

mol clin onc

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Abstract. Malignant mesothelioma of the tunica vaginalis testis is an extremely rare tumor without specific clinical manifestations, mainly including hydrocele formation and a painless mass. We herein present the case of a patient with hydrocele of the left testis, without any other complaints. Tunica vaginalis subinvolution was performed, and postoperative pathological examination revealed a malignant mesothelioma arising from the left tunica vaginalis testis. Whole-body positron emission tomography-computed tomography (PET-CT) and subsequent abdominal and pelvic magnetic resonance imaging (MRI) revealed no evidence of local lymphadenopathy. Radical left orchiectomy was performed after the pathological diagnosis. The pathological examination after the second surgery demonstrated that the tumor had invaded the adjacent periorchium and spermatic cord, but there was no evidence of local lymph node metastasis. Pemetrexed and cisplatin were administered at a dose of 900 and 130 mg, respectively, on the first day of a 28-day cycle. After 6 months of therapy, the disease had not progressed on abdominal and pelvic PET-CT and MRI. The patient was still followed up in our urology outpatient clinic at the time of the present report. Although testicular hydrocele is a common and easily diagnosed condition, detailed medical history and physical examination are required. Thus, when clinicians encounter patients with testicular hydrocele, a variety of possible causes must be considered, including testicular or paratesticular tumors, even rare tumors such as mesothelioma of the tunica vaginalis testis.

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Section: Discussionmentioning

confidence: 99%

Malignant mesothelioma of the tunica vaginalis testis: A case report and literature review

Zhang

et al. 2017

mol clin onc

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“…Mezotelyoma, paratestiküler alanda, genellikle tunika vajinalisten köken alan, lokal nüks ve metastazlarla seyreden agresif bir tümördür (14,26,27). Spermatik kord ve epididimden de gelişebileceği bilinmektedir (14,26).…”

Section: Mezotelyomaunclassified

“…Spermatik kord ve epididimden de gelişebileceği bilinmektedir (14,26). Genellikle altıncı dekattan sonra görülür.…”

Section: Mezotelyomaunclassified

“…Çocukluk çağında asbest maruziyeti bilinen risk faktörü olmasına rağmen risk faktörü taşımayanlarda da gelişen mezotelyoma olguları mevcuttur (14,26). Hastaları kliniğe başvurmaya en sık iten bulgu skrotal şişlik ve tekrarlayan dirençli hidrosel gelişimidir (14,26,27). Bu hastalarda USG ile vaskülarizasyon artışı ve çeperde vejetasyonların tespit edilmesi mezotelyomayı akla getirmelidir (7,27).…”

Section: Mezotelyomaunclassified

“…Çevre yumuşak dokuları, testisi ya da deriyi infiltre edebilir. En sık epitelyal ve bifazik formu izlenir, saf sarkomatöz formu daha nadirdir (14,26). Mikroskopik olarak, epitelyal formunda tek ya da çok sıralı atipik mezotelyal hücreler genelde papiller ve tübülopapiller patern oluştururken, solid tabakalar dahil her türlü glandüler yapılanmayı izlemek mümkündür (14,28).…”

Section: Mezotelyomaunclassified

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