Malignant Mesenchymal Tumor of the Prostate: A Case Report

Abstract

SUMMARYNonepithelial tumors of the prostate represent <1% of all prostate tumors. A rare soft tissue sarcoma is common in the lower extremities and can occur anywhere in the body. Malignant mesenchymal tumors of the prostate are rarely observed. The histogenesis of malignant mesenchymal tumors that have totipotential differentiation capacity and arise from primitive mesenchymal cells is still unknown. These are malignant soft tissue sarcomas including ≥2 different mesenchymal elements in addition to the fibrosarcomatous elements. This type of tumors can occur anywhere within the body; the most frequently reported sites are the retroperitoneal cavity and lower extremity. They may occur in the heart, mediastinum, pleura, liver, eyes, bones, larynx, thyroid, testis, uterus, and bladder. The malignant potential is high and the progression of these tumors is rapid. There is mass in the prostate; however, when the prostate-specific antigen levels are normal, differential diagnoses should be considered. Although the main treatment for this disease is surgery, chemotherapy and/or radiotherapy can be applied. We present a rare case of malignant mesenchymal tumor of the prostate.