Malignant Meningioma Manifesting in the Nose and its Surgical Approach

Hiranandani, L. H.; Hiranandani, G. K.

doi:10.1017/s0022215100068596

Cited by 1 publication

(1 citation statement)

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“…[4][5][6]19 Ectopic arachnoid tissue, gene mutation due to cytostatic radiotherapy, and pharmacological therapy can cause these tumors to appear at those atypical primary locations. 15 Recurrence of benign and malignant meningiomas, even after so-called total tumor removal, is a well-described problem.…”

Section: Discussionmentioning

confidence: 99%

Seeding of malignant meningioma along a surgical trajectory on the scalp

Lüdemann¹,

Obler²,

Tatagiba³

et al. 2002

Journal of Neurosurgery

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The authors report the case of an 11-year-old boy with a malignant meningioma of the right frontal meninges. The tumor was asymptomatic, despite visible exophytic extracranial growth. Neuroimaging demonstrated an en plaque meningioma bulging into the brain. Six months after the tumor had been totally removed by surgery, an isolated subcutaneous metastasis developed at the right preauricular area of the scalp, originating at the scar left by the first surgery. After removal of this metastasis, radiotherapy was conducted. To date the follow-up examinations have not revealed any additional metastases. To the best of the authors' knowledge, this is the first report of a seeding of a subcutaneous metastasis in a child with a malignant meningioma. The authors review the literature with reference to malignant meningiomas and their formation of metastasis. In cases of malignant meningiomas, piecemeal tumor removal carries the risk of iatrogenic cell dissemination even when precautions are taken.

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Section: Discussionmentioning

confidence: 99%