Malignant melanoma of the rectum presenting as orbital metastasis

Narayanan, Natasha; Padwal, Utkarsha; Gopinathan, Indumati; Pathak, Rima; Nair, Akshay Gopinathan

doi:10.4103/ijo.ijo_847_20

Cited by 2 publications

(1 citation statement)

References 11 publications

(3 reference statements)

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“…Malignant melanoma of the rectum typically presents in the fifth or sixth decade of life with nonspecific complaints such as rectal bleeding or anal pain. 5 In front of clinical nonspecific features, imaging plays a crucial role in the management of ARM, thereby, fixing local and distant extension workup. MRI is used to evaluate local involvement as it shows habitually a bulky intraluminal polypoid mass in the anorectum with the mass showing T1 hyperintensity, high or mixed signal T2 intensity, hyperenhancement, minimal perirectal or anal infiltration, and lymphadenopathy.…”

Section: Discussionmentioning

confidence: 99%

Organ preservation in anorectal melanoma: A tempting challenge—a case report

Trabelsi,

Kammoun,

Inoubli

et al. 2023

SAGE Open Medical Case Reports

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Melanoma arising from melanocytes is an uncommon neoplastic lesion, with rare occurrences in anorectal mucosa. While mucosal melanomas constitute a small portion of all melanomas, anorectal cases are even rarer and present with aggressive behavior and poor prognosis. Surgical management is central, with evolving debates regarding optimal approaches. We present a case of a 60-year-old woman with anorectal melanoma. She complained of rectal bleeding and weight loss. Clinical examination and pelvic magnetic resonance imaging revealed a 3-cm budding lesion on the anterior rectal wall. Colonoscopy identified a pedunculated anorectal tumor of 3 cm, situated 4 cm from the anal margin. A biopsy led us to a malignant lesion: anorectal melanoma. Pelvic imaging displayed a localized tumor, prompting wide local excision with millimetric negative margins. These resection margins were estimated insufficient, even in front of R0 resection. Thus, and after multidisciplinary discussion, we opted for abdominoperineal resection after wide local excision. Lymph nodes were biopsied, confirming no residual tumor. Follow-up exhibited no recurrence at 1 year. Our case emphasizes the pivotal role of surgical strategy in managing anorectal melanoma, challenging the paradigm of organ preservation. Despite therapeutic progress, surgery remains integral, contributing to improved outcomes and addressing the metastatic potential inherent to this disease.

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Section: Discussionmentioning

confidence: 99%

Organ preservation in anorectal melanoma: A tempting challenge—a case report

Trabelsi,

Kammoun,

Inoubli

et al. 2023

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

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Metastatic anorectal melanoma presenting with bilateral orbital mass – A rare case

Agrawal,

Meel,

Pushker

et al. 2024

Indian Journal of Ophthalmology - Case Reports

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Due to the increased longevity of patients and advances in diagnostic modalities, an increase in the prevalence of patients with orbital metastasis is being observed. Here, we report a lady in her 40s who presented with complaints of painless protrusion of the left eyeball with restricted motility and reduced vision. She gave history of surgery for hemorrhoids. Based on clinical and imaging findings, a diagnosis of orbital metastasis was made. Thorough systemic evaluation revealed the primary tumor to be a melanoma of anorectal origin with widespread metastasis. An orbital surgeon should keep high suspicion for metastasis while working up cases of orbital malignancy, especially in the elderly population.

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Malignant melanoma of the rectum presenting as orbital metastasis

Cited by 2 publications

References 11 publications

Organ preservation in anorectal melanoma: A tempting challenge—a case report

Organ preservation in anorectal melanoma: A tempting challenge—a case report

Metastatic anorectal melanoma presenting with bilateral orbital mass – A rare case

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