Malignant melanoma of the oral cavity—an increasing clinical diagnosis?

Smyth, A.G.; Ward-Booth, R.P.; To, Edward W.H.; Avery, B.S.; Lane, Ayresome Greeen

doi:10.1016/0266-4356(93)90145-m

Cited by 27 publications

(24 citation statements)

References 36 publications

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“…Rapini et al (1985) stated that these melanotic patches probably represent the radial growth phase of the tumour which may last for 10-15 months. Oral melanoma colour varies (Ohashi et al, 1992;Smyth et al, 1993) and many pigmented lesions have to be considered for differential diagnosis (Manganaro et al, 1995).…”

Section: Oral Mucosal Melanoma 253mentioning

confidence: 99%

Oral mucosal melanoma: a series of case reports

Garzino-Demo

Fasolis

Terra

et al. 2004

Journal of Cranio-Maxillofacial Surgery

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Section: Oral Mucosal Melanoma 253mentioning

confidence: 99%

Oral mucosal melanoma: a series of case reports

Garzino-Demo

Fasolis

Terra

et al. 2004

Journal of Cranio-Maxillofacial Surgery

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“…Complete excision with a wide margin is the treatment of choice whenever possible. In the case of malignant melanoma affecting the palate, subperiosteal excision sparing the hard palate is recommended, thus limiting mutilation, especially in light of a very poor overall prognosis (6,15). In the present case, a more radical approach including right maxillectomy had to be taken due to the extension of the lesion into the maxillary sinus.…”

Section: Discussionmentioning

confidence: 89%

Acral Lentiginous Melanoma of the Palate: Report of a case

2004

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“…[1617] The lesion is three times more common in men than in women. In the oral cavity, malignant melanoma almost exclusively occurs in the palate and maxillary gingiva with an incidence of 80% and 91.4%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Oral malignant melanoma: A silent killer?

Padhye¹,

D'souza²

2011

J Indian Soc Periodontol

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Oral malignant melanomas are extremely rare lesions and occur commonly in the maxillary gingiva more frequently on the palate with fewer incidences in the mandibular gingiva. Though these lesions are biologically aggressive, they often go unnoticed since they are clinically asymptomatic in the early stages and usually present merely as a hyperpigmented patch on the gingival surface. These lesions if diagnosed at an early in situ stage are potentially curable and definitely have a better prognosis, but unfortunately as they are clinically asymptomatic, it results in delayed diagnosis thus making the prognosis extremely poor. This paper presents the case of a patient who visited our department with the complaint of darkened patches on the gums and his concern was purely aesthetic. There were no symptoms associated with the hyperpigmented lesions and hence the patient did not approach us earlier. When the lesions grew larger and were unsightly, the patient has seeked dental advice. Histopathologic investigation confirmed the diagnosis as ‘Oral Malignant Melanoma’. Though aggressive therapy was instilled immediately, unfortunately, the patient succumbed to death within a few months after diagnosis as the lesion was highly invasive. Due to the biologically aggressive but clinically silent nature of progression of the lesion, the importance of maintaining a high index of suspicion and early detection and diagnosis for any pigmented gingival lesions cannot be overemphasised. Diagnosis must be based on thorough detailed history and valid histologic evidence.

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Malignant melanoma of the oral cavity—an increasing clinical diagnosis?

Cited by 27 publications

References 36 publications

Oral mucosal melanoma: a series of case reports

Oral mucosal melanoma: a series of case reports

Acral Lentiginous Melanoma of the Palate: Report of a case

Oral malignant melanoma: A silent killer?

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