Malignant melanoma of the lung: case series

Postrzech-Adamczyk, Katarzyna; Chabowski, Mariusz; B, Głuszczyk-Ferenc; Wodzińska, Agnieszka; Muszczyńska-Bernhard, Beata; Szuba, Andrzej; Janczak, Dariusz

doi:10.5114/kitp.2015.50575

Cited by 5 publications

(1 citation statement)

References 7 publications

(14 reference statements)

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“…The diagnosis criteria of PMML have been clearly defined by Jensen and Egedorf [11], with only minor modifications, including the clinical characteristics, radiologic features, and pathological diagnosis [12]. The prerequisite of the clinical characteristics includes no previously resected pigmented skin lesion, absence of any other detectable tumours at the time of diagnosis, no history of a melanoma in other organs at time of surgery, and solitary lung cancer.…”

Section: Discussionmentioning

confidence: 99%

Primary malignant melanoma of the lung: a case report and literature review

et al. 2020

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Background: Malignant melanoma (MM) generally presents as a primary neoplasm of the skin, and most MM cases of the respiratory system are metastatic. Primary MM of the lung (PMML) is quite rare, and its diagnosis is relatively difficult. Case presentation: We report the case of a 57-year-old male patient with PMML who denied any history of tumours. His initial complaint was frequent coughs with bloody sputum for 4 days. Chest radiography demonstrated a highdensity shadow in the lower lobe of the right lung, which was suspected to be a large space-occupying lesion on subsequent computed tomography (CT) and to be a hypermetabolic tumour by positron emission tomography-CT. To confirm the diagnosis, exploratory surgery was performed. Finally, we confirmed the diagnosis of PMML. Conclusions: PMML is extremely rare and easily misdiagnosed as lung cancer. Because of its morphological and immunophenotypic variations, the diagnosis of PMML remains difficult. This case report discusses the diagnosis and case management of a patient while referring to the existing literature.

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Section: Discussionmentioning

confidence: 99%

Primary malignant melanoma of the lung: a case report and literature review

et al. 2020

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Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review

Kyriakopoulos

Zarkavelis

Andrianopoulou

et al. 2017

Case Reports in Oncological Medicine

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Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are extremely rare. Published data on primary pulmonary malignant melanomas are limited. Up to now 40 relevant cases have been reported in the English literature. Herein, we report a case of a 56-year-old female patient who presented with intracranial metastases due to primary pulmonary melanoma. She underwent bronchoscopy and died 5 months after the initial diagnosis despite the administered biochemotherapy and subsequent immunotherapy. To establish the diagnosis of primary pulmonary malignant melanoma, any extrapulmonary origin was excluded by detailed examination and radiographic imaging. Moreover, an extensive review of the literature regarding this rare entity has been performed.

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Primary Pulmonary Malignant Melanoma Found While Evaluating New Onset Cough: A Case Presentation and Literature Review

Rodriguez

Uddin

Nasr

2019

Case Reports in Pulmonology

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Malignant melanoma is a nonepithelial neoplasm of melanocytes. It is tremendously rare for this condition to primarily involve the respiratory tract, accounting only for 0.01% of the lung malignancies. It often presents as a solitary nodule provoking mass effect and/or obstructive symptom. It most commonly affects patients 50 years old and older, with no gender predilection. Complete surgical excision is the treatment of choice; nevertheless, chemotherapy or radiation might be necessary depending on tumor location and/or metastasis status. Recently, biochemotherapy and immunotherapy have emerged as promising treatment modalities. We present a case of Primary Pulmonary Malignant Melanoma (PPMM) in a 76-year-old male with no previous personal or family history of cancer who presented with new onset nonproductive cough. We also present an analysis with high yield points summarizing clinical features, diagnostic workup, and management of PPMM. Finally, we post a table summarizing all the cases ever reported in English literature.

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Malignant melanoma of the lung: case series

Cited by 5 publications

References 7 publications

Primary malignant melanoma of the lung: a case report and literature review

Primary malignant melanoma of the lung: a case report and literature review

Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review

Primary Pulmonary Malignant Melanoma Found While Evaluating New Onset Cough: A Case Presentation and Literature Review

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