Malignant Melanoma Among Negroes and Latin Americans in Texas

Macdonald, Eleanor J.

doi:10.1016/b978-1-4832-2888-4.50016-4

Cited by 19 publications

(7 citation statements)

References 3 publications

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“…Urtega and Pack [23] found only one negro in their series of 49 patients. However, in a recent survey, no significant differences in the incidence of the disease among Negroes, Latin Americans or Anglo-Americans was found in Texas [16]. Our findings are similar to this last report, and no difference in the frequency of malignant melanoma was found between the fair-skinned and dark-skinned groups in our population.…”

Section: Discussionsupporting

confidence: 82%

Malignant Melanoma

Biran¹,

Hochman²,

Walach³

1973

Oncology

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The clinical experience is described with 232 patients suffering from malignant melanoma. Various therapeutic procedures were applied, the largest group consisting of 82 patients treated by surgical excision followed by local irradiation. The next large group included 66 patients treated by local surgical excision alone, while the third group consisted of 22 patients treated by local surgery followed by irradiation of the lymphatic pathway between the primary tumor and the regional lymph nodes and the nodes themselves. The best 5-year survival was achieved in the last-mentioned group, 45% for stage I and II patients.

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Section: Discussionsupporting

confidence: 82%

Malignant Melanoma

Biran¹,

Hochman²,

Walach³

1973

Oncology

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“…None of our patients who had re-excision of the local recurrence survived 5 years. Similar poor survival has been reported by others following local recurrence.4~ [18][19][20][21][22][23][24][25][26][27][28][29][30][31] Generally speaking, patients with clinically suspicious nodes at the time of initial surgery have a very poor prognosis. I n the absence of distant metastases, however, it is generally agreed that a lymph node dissection should be performed.…”

Section: Discussionmentioning

confidence: 61%

Clinical study of forty-nine patients with malignant melanoma

Lehman

Cross

Richey

1966

Cancer

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A study of 49 patients with malignant melanoma of the skin occurring over an 18‐year period is presented. The over‐all 5‐year survival was 43%. The prognosis was uniformly better for females and for lesions less than one cm. A poor prognosis was associated with primary lesions on the trunk, ulceration or hemorrhage of the primary and clinically and microscopically positive nodes. The authors conclude that a wide local excision of the primary lesion, including a 3 to 5 cm margin of skin, combined with an in‐continuity regional lymph node dissection should be the treatment of choice.

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“…The mean incidence among white populations was over 3-fold greater than that of nonwhites, supporting the suggestion that skin pigmentation protects against melanoma. However, as other authors have reported (MacDonald, 1959;Lewis, 1967), solme non0-White p)optlIlations experieniced a relatively high incidence, so that skin colour may not be the only factor governing melacnoma incidence.…”

Section: Resultsmentioning

confidence: 79%

“…Indeed many of the tumours among black Africans may be unrelated to solar exposure since they occur on the unexposed sole of the foot (Oettle, 1]966;Camain et al, 1972;MacDonald, 1959;Lewis, 1967;Fleming et al, 1975;Davies et al, 1968). One study has reported that the tumours are most frequent on the weight-bearing areas of the sole, indicating that trauma is the important factor (Oettle, 1966).…”

mentioning

confidence: 99%

Racial differences in melanoma incidence

Crombie¹

1979

Br J Cancer

113

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Summary.-The incidences of malignant melanoma recorded by 59 populationbased cancer registries were investigated to determine the effects of racial and skincolour differences. White populations exhibited a wide range of melanoma incidences and females commonly, though not invariably, had a higher incidence than males. Non-white populations experienced in general a much lower incidence of melanoma although there was some overlap of white and non-white rates. No predominant sex difference emerged among non-whites.Populations of African descent were found to have a higher incidence than those of Asiatic origin, but it was concluded that this was due largely to the high frequency of tumours among Africans on the sole of the foot. A clear negative correlation between degree of skin pigmentation and melanoma incidence emerged for the exposed body sites. These data provide strong support for the hypotheses that UV radiation is a major cause of malignant melanoma and that melanin pigmentation protects against it. Further research is required to elucidate the aetiology of melanoma of the sole of the foot.

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Malignant Melanoma Among Negroes and Latin Americans in Texas

Cited by 19 publications

References 3 publications

Malignant Melanoma

Malignant Melanoma

Clinical study of forty-nine patients with malignant melanoma

Racial differences in melanoma incidence

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