Malignant Lymphoma of the Paranasal Sinuses

Sofferman, Robert A.; Cummings, Charles W.

doi:10.1001/archotol.1975.00780340019004

Cited by 60 publications

(16 citation statements)

References 15 publications

(2 reference statements)

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“…In the Western World this site accounts for 0.2% to 2.0% of all NHL. 2,3 The majority of these lymphomas are of large B‐cell subtype, 4–13 contrasting with those in the Far East 14–20 and South America, 21 which are predominantly of T‐cell subtype (particularly of the natural killer T‐cell type showing CD56 positivity). Primary NHL lymphoma disease in the West is more common in elderly men and is located in the paranasal sinuses, as distinct from the Far East manifestation of the disease, which presents at a younger age and is located in the nasal cavity.…”

Section: Introductionmentioning

confidence: 99%

Non‐Hodgkin's Lymphoma of the Sinonasal Tract

et al. 2000

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Objectives: A review of the presenting features, management, and outcome of extranodal nonHodgkin's lymphoma (NHL) of the sinonasal tract during a 10-year period in Nottingham, UK. Study Design: Twenty-four patients received a diagnosis of extranodal NHL of the nasal cavity, paranasal sinuses, or both, from 1987 to 1996. The patients' data were collected prospectively in the Nottinghamshire Lymphoma Registry. Methods: All patients' records and their histology were reviewed along with data entered into the Nottinghamshire Lymphoma Registry, noting the patient's age, sex, presenting symptoms and signs, staging, computed tomography findings, histology, treatment, complications, and outcome. Results: The 24 patients with extranodal NHL of the sinonasal tract represent 1.63% of the 1,457 patients with NHL seen in the 10-year period of this study in Nottinghamshire. The median age was 72 years (range, 42-96 y), with a male dominance (male-to-female ratio: 15:9). Most patients presented with nonspecific nasal symptoms such as nasal obstruction and epistaxis. Only one patient had a relapse involving the central nervous system after treatment. All the histology was reviewed and showed a predominance of large B-cell subtype (21 patients). The overall 5-year survival was 40% (95% CI, 19%-61%) and 33% for 10-year (95% CI, 12%-54%). The cause-specific survival at 5 years and 10 years was 62% (95% CI, 39%-86%). Conclusions: A high degree of suspicion and appropriate use of computed tomography scans and surgical biopsy are the keys to the management of NHL.

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Section: Introductionmentioning

confidence: 99%

Non‐Hodgkin's Lymphoma of the Sinonasal Tract

et al. 2000

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“…Lymphomas originating in the nasal cavity and/or paranasal sinuses are very uncommon, with the reported incidence varying between 0.3 and 13% 8 , 11 , 16 . The incidence of lymphoma in relation to other malignant tumours of the nasal cavity and the paranasal sinuses varies between 10 and 29% 17 , 18 . Lesions presenting in the nasal cavity and the paranasal sinuses are often clinically interpreted as squamous cell carcinoma due to the non‐specificity of the clinical findings, and because of its more frequent incidence in the head and neck 18 .…”

Section: Discussionmentioning

confidence: 99%

Adult Head and Neck Lymphomas in Papua New Guinea: A Retrospective Study of 70 Cases

Dubey¹,

Sengupta

Kaleh³

et al. 1999

Aust. N.Z. J. Surg.

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“…Benigne Neoplasien unterscheiden sich, neben dem meist nichtinfiltrierenden Wachstum, auch durch mögliche systemische Wirkungen [8], können aber auch durch zunehmende Nasenatmungsbehinderung symptomatisch werden [0, 27,29]. Eine sichere Diagnose von kindlichen Nasennebenhöhlenmalignomen wird oft nur durch eine enge Kooperation von KopfHals-Chirurgie, Pathologie, Kinderhäma-toonkologie und Radiologie ermöglicht.…”

Section: Typen Kindlicher Malignomeunclassified

“…war inital alio loco die klinische Verdachtsdiagnose einer chronische Sinusitis sogar histologisch bestätigt worden. Bei malignen Lymphomen treten selten auch Epistaxis, Exophthalmus, Perforation des harten Gaumens, Hirnnervenausfälle und B-Symptome auf [, 6, 5, 9, 25,27,28].…”

Section: Myelosarkomunclassified