Malignant Irradiation for Benign Conditions

Cannon, Bradford; Randolph, Judson G.; Murray, Joseph E.

doi:10.1056/nejm195901292600501

Cited by 62 publications

(25 citation statements)

References 4 publications

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“…The mean interval between exposure to radiation and tumor develop ment was 2 1 years. The longest interval in that series was 64 years, while the longest interval recorded in the literature was between 30 and 50 years [11][12][13][14][15][16]. Thirty-five patients died as a result of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma – 70 Years after Irradiation

Ophir

Wolf²,

Tamir³

et al. 1992

Dermatology

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Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma – 70 Years after Irradiation

Ophir

Wolf²,

Tamir³

et al. 1992

Dermatology

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“…In 1925 more pages were given to describing RT indications of various benign diseases than for cancer in the most comprehensive textbook for RT of that time [19]. The use of RT has decreased considerably as reports about carcinogenesis due to ionizing irradiation [1,4] and new and better systemic and topical treatments have become available. However, e.g.…”

Section: Discussionmentioning

confidence: 99%

Long-term Results of Radiotherapy in Patients with Chronic Palmo-plantar Eczema or Psoriasis

Sumila¹,

Notter²,

Itin

et al. 2008

Strahlenther Onkol

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Background and Purpose: Radiotherapy (RT) is well accepted for therapy-refractory palmo-plantar eczema or psoriasis, despite of lacking evidence regarding beneficial long term effects. Furthermore, the optimal irradiation dose is unknown. We evaluated the outcome of RT with two different RT single/total dose (SD/TD) treatment policies. Patients and Methods: 28 consecutive patients with therapy-refractory eczema (n = 22) or psoriasis (n = 6) of palms and/or soles were irradiated twice a week either with a D max SD of 1 Gy (6/98-5/03; median TD: 12 Gy) or 0.5 Gy (6/03-7/04; median TD: 5 Gy). Median age was 52 years (27-71), median follow-up 20 months (4-76). Totally 88 regions were treated, 49 with 1 Gy, 39 with 0.5 Gy SD. Eight different symptoms were scored from 0 (absent) -3 (severe), giving a possible sum score of 0-24. Patients' rating of RT result was also documented (worse/stable/better/complete remission). Results: The sum score was 15 (6-23) before RT, 2 (0-16) at the end of RT, and 1 (0-21) at last follow-up, respectively. The improvement was highly significant in both treatment regimens. Better or complete remission by the patients were reported in 44 and 39 (= 83 out of 88) localisations, that was often stable during the follow-up. 5 (6%) regions in 3 (11%) patients didn't benefit from RT. Conclusion: RT reveals excellent results in palmo-plantar eczema or psoriasis. We recommend a SD of 0.5 Gy twice a week up to a TD of 4-5 Gy.

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“…Über objektive Röntgenschäden nach hochdosierter Bestrahlung von Plantarwarzen berichten unter anderen Sauerbrey [15], G ottron [5], Cannon [1] und H ess [8].…”

Section: Diskussionunclassified

“…Cannon [1] berichtet in seinem Artikel «Maligne Bestrahlung für be nigne Affektionen » über 32 Fälle von zumeist mehrmals bestrahlten Plan tarwarzen und schweren Röntgenspätschäden.…”

Section: Diskussionunclassified

Spätresultate von bestrahlten Plantarwarzen

Faessler¹,

Krebs²

1974

Dermatology

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100 of 250 patients treated for plantar warts with an irradiation dosage of 3–4 × 1000 r/ 50 kV/1.0 mm Al were reexamined after an average interval of 11.3 years. The following results were obtained in the 91 patients who were cured by this treatment: 7 patients showed serious post-irradiation damage; in 2 patients recurrence had taken place; 31 revealed slight X-ray changes of the skin, whereas in 51 patients no pathological changes by irradiation could be detected

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Malignant Irradiation for Benign Conditions

Cited by 62 publications

References 4 publications

Squamous Cell Carcinoma – 70 Years after Irradiation

Squamous Cell Carcinoma – 70 Years after Irradiation

Long-term Results of Radiotherapy in Patients with Chronic Palmo-plantar Eczema or Psoriasis

Spätresultate von bestrahlten Plantarwarzen

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