Malignant hypertension and retinopathy in a western lowland gorilla (<i>Gorilla gorilla gorilla</i>)

Niemuth, Jennifer N.; Voe, Ryan S. De; Jennings, Sydney; Loomis, Michael R.; Troan, Brigid V.

doi:10.1111/jmp.12114

Cited by 6 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…185 She developed acute blindness due to bilateral retinal detachment and intraocular hemorrhage. Cataracts were also present.…”

Section: Deterioration Of Special Sensesmentioning

confidence: 99%

“…Retinal disease due to vascular lesions was described in a 34 yo female gorilla with a history of hypertension (based on measurements taken during anesthetic events). 185 She developed acute blindness due to bilateral retinal detachment and intraocular hemorrhage. Cataracts were also present.…”

Section: Deterioration Of Special Sensesmentioning

confidence: 99%

“…In a 34 yo female, there was marked left ventricular hypertrophy (free wall 2.6 cm thick) and median hypertrophy with ''onion skin fibrosis'' in small arteries in the retina, choroid, and meninges of the brain, kidney, and heart. 185 In a 28 yo male, hypertension was documented over a 2 y period. 171 He developed congestive heart failure and died under anesthesia.…”

Section: Hypertensionmentioning

confidence: 99%

See 2 more Smart Citations

Comparative Pathology of Aging Great Apes

2015

View full text Add to dashboard Cite

The great apes (chimpanzees, bonobos, gorillas, and orangutans) are our closest relatives. Despite the many similarities, there are significant differences in aging among apes, including the human ape. Common to all are dental attrition, periodontitis, tooth loss, osteopenia, and arthritis, although gout is uniquely human and spondyloarthropathy is more prevalent in apes than humans. Humans are more prone to frailty, sarcopenia, osteoporosis, longevity past reproductive senescence, loss of brain volume, and Alzheimer dementia. Cerebral vascular disease occurs in both humans and apes. Cardiovascular disease mortality increases in aging humans and apes, but coronary atherosclerosis is the most significant type in humans. In captive apes, idiopathic myocardial fibrosis and cardiomyopathy predominate, with arteriosclerosis of intramural coronary arteries. Similar cardiac lesions are occasionally seen in wild apes. Vascular changes in heart and kidneys and aortic dissections in gorillas and bonobos suggest that hypertension may be involved in pathogenesis. Chronic kidney disease is common in elderly humans and some aging apes and is linked with cardiovascular disease in orangutans. Neoplasms common to aging humans and apes include uterine leiomyomas in chimpanzees, but other tumors of elderly humans, such as breast, prostate, lung, and colorectal cancers, are uncommon in apes. Among the apes, chimpanzees have been best studied in laboratory settings, and more comparative research is needed into the pathology of geriatric zoo-housed and wild apes. Increasing longevity of humans and apes makes understanding aging processes and diseases imperative for optimizing quality of life in all the ape species.

show abstract

“…185 She developed acute blindness due to bilateral retinal detachment and intraocular hemorrhage. Cataracts were also present.…”

Section: Deterioration Of Special Sensesmentioning

confidence: 99%

Section: Deterioration Of Special Sensesmentioning

confidence: 99%

Section: Hypertensionmentioning

confidence: 99%

See 1 more Smart Citation

Comparative Pathology of Aging Great Apes

2015

View full text Add to dashboard Cite

show abstract

“…Normal ocular anatomy of the western lowland gorilla has been previously reported . Reported ophthalmic disease includes cataract, hypertensive retinopathy, macular degeneration, and keratitis caused by Onchocerca volvulus . To the best of the authors’ knowledge, this is the first report of vernal‐like conjunctivitis in a western lowland gorilla.…”

Section: Introductionmentioning

confidence: 63%

Vernal‐like conjunctivitis in a western lowland gorilla (Gorilla gorilla gorilla)

Hopper¹,

Holding²,

Scurrell

et al. 2017

Veterinary Ophthalmology

View full text Add to dashboard Cite

Case description A 17-year-old female western lowland gorilla presented with bilateral ocular discharge, conjunctivitis, and rhinitis that was investigated and treated over a 34-month period. Clinical findings, diagnostic results, treatment, and follow-up are described. Clinical finding A mild intermittent mucoid ocular discharge was initially noted. 10 months later, conjunctival hyperemia and thickening developed and progressed rapidly to a mass-like lesion covering the right eye. Hematology revealed eosinophilia. Conjunctival cytology revealed eosinophils and neutrophils, and histopathology revealed a chronic proliferative eosinophilic conjunctivitis. 21 months after, the ocular lesions were investigated the gorilla developed masses within both external nares. Histopathology of the nasal lesions revealed chronic-active eosinophilic rhinitis. Treatment and outcome Treatment of the gorilla was based on protocols recommended for human patients. Protocols for mild, moderate, and finally severe disease were used, involving topical and oral combinations of treatments. The gorilla eventually responded to systemic immunosuppressant therapy recommended for severe refractory disease. Clinical significance To the authors' knowledge, this is the first reported case of vernal-like conjunctivitis in a western lowland gorilla. History and signalmentA 17-year-old female western lowland gorilla (weight 85.7 kg; Gorilla gorilla gorilla) developed bilateral ocular discharge, conjunctivitis, and rhinitis that was investigated and treated over a 34-month period. The only prior medical history was a single episode of mastitis after giving birth 3 years previously.

show abstract

Ophthalmology of Primatomorpha: Lemurs, Tarsiers, Monkeys, Apes, and Relatives

Thomasy

2022

Wild and Exotic Animal Ophthalmology

View full text Add to dashboard Cite

Malignant hypertension and retinopathy in a western lowland gorilla (Gorilla gorilla gorilla)

Abstract: We describe a case of naturally occurring hypertensive encephalopathy and retinopathy in a gorilla.

Cited by 6 publications

References 13 publications

Comparative Pathology of Aging Great Apes

Comparative Pathology of Aging Great Apes

Vernal‐like conjunctivitis in a western lowland gorilla (Gorilla gorilla gorilla)

Ophthalmology of Primatomorpha: Lemurs, Tarsiers, Monkeys, Apes, and Relatives

Contact Info

Product

Resources

About