Malignant fibrous histiocytoma of the spine causing spinal neural foramen widening

Karantanas, A. H.; Hytiroglou, Prodromos; Zibis, Aristeidis; Markonis, A.; Papadimitriou, Constantine S.

doi:10.1016/s0895-6111(00)00024-0

Cited by 7 publications

(13 citation statements)

References 7 publications

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“…3 MFH of bo ne was first des cri bed as a se pa ra te en tity in 1972. 5 It is an un com mon tu mo r seen in ol der age gro ups.…”

Section: Discussionmentioning

confidence: 99%

“…5 The vast ma jo rity of os se o us MFH oc cur in long bo nes, with the fe mur, ti bi a, and hu me rus ac co un ting for ap pro xi ma tely 75% of all ca ses, but the spi ne is a very un com mon si te of lo ca li za ti on. 3 Only 12 pri mary spi nal MFH ca ses ha ve be en descri bed. [1][2][3][4] Pa in re li ef is seen af ter la mi nec tomy, but may re cur with furt her tu mo r growth.…”

Section: Discussionmentioning

confidence: 99%

“…3 Only 12 pri mary spi nal MFH ca ses ha ve be en descri bed. [1][2][3][4] Pa in re li ef is seen af ter la mi nec tomy, but may re cur with furt her tu mo r growth. Me tas ta ses oc cur usu ally to lung or ot her bo nes, bra in me tasta ses oc cur ra rely.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] Primary spinal bony involvement is exceedingly rare. [2][3][4] Metastases occur predominantly in the lung (82%), lymph nodes (32%), liver and bone (15% each). We discussed clinical features, radiologic findings and mode of treatment in our MFH patient.…”

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confidence: 99%

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Primary Malignant Fibrous Histiocytoma in Lumbar Vertebra: Case Report

Öksüz¹,

Deniz²,

Köseoğlu³

2011

Turkiye Klinikleri J Med Sci

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1570alignant fibrous histiocytoma (MFH) is a well recognized malignancy. It is classified by World Health Organization as soft tissue tumor for pleomorphic soft-tissue sarcoma showing no specific line of differentiation.1,2 MFH most commonly involves the deep soft tissues of the extremities, mainly the thigh, with a predilection for men. [1][2][3] Primary spinal bony involvement is exceedingly rare.2-4 Metastases occur predominantly in the lung (82%), lymph nodes (32%), liver and bone (15% each). We discussed clinical features, radiologic findings and mode of treatment in our MFH patient.Primary Malignant Fibrous Histiocytoma in Lumbar Vertebra: Case Report A AB BS S T TR RA AC CT T A 71-ye ar-old man with a cli ni cal pic tu re of a low back pa in ra di a ting to right leg cau sed by pri mer ma lig nant fib ro us his ti ocy to ma of L2 ver teb ra was re por ted in this pa per. Ma lig nant fib ro us his ti ocy to ma is clas si fi ed as soft tis su e tu mo r for ple o morp hic soft-tis su e sar co ma sho wing no spe ci fic li ne of dif fe ren ti a ti on. Ma lig nant fib ro us his ti ocy to ma most com monly in vol ves the deep soft tis su es of the ex tre mi ti es, ma inly the thigh, with a pre di lec ti on for men. However it is rarely se en in ver teb rae. In our ca se, lung and mul tip le bra in me tas ta ses we re se en at the sa me ti me. The pa ti ent was ope ra ted for ne u ral de com pres si on and ra di ot he rapy and che mot he rapy we re perfor med af ter di ag no sis. The sur vi val was only thre e months.K Ke ey y W Wo or rd ds s: : His ti ocy to ma, ma lig nant fib ro us; low back pa in; spi ne Ö ÖZ ZE ET T Bu ma ka le de 71 ya şın da ki has ta da bel ve sağ ba ca ğa ya yı lan ağ rı kli ni ği ile or ta ya çı kan L2 ver teb ra da olan pri mer ma lign fib röz his ti o si to ma ra por edil miş tir. Ma lign fib röz his ti o si to ma, yumu şak do ku tü mör le ri için de ple o mor fik yu mu şak do ku sar ko mu ola rak sı nıf lan dı rı lır ve her hangi bir spe si fik di fe ran si as yon gös ter mez. Pri mer ma lign fib röz his ti o si to ma sık lık la eks tre mi te le rin de rin yu mu şak do ku kıs mın da ve özel lik le uy luk ta gö rül mek te dir. Ma lign fib röz his ti o si to ma er kekler de da ha sık göz len mek te dir. Bi rin cil ver teb ra tu tu lu mu na di ren gö rül mek te dir ve li te ra tür de rapor edi len ver teb ra tu tu lu mu çok az dır. Bu ol gu da ay nı za man da ak ci ğer ve çok lu be yin me tas taz la rı tes pit edil miş tir. Has ta nö ral do ku de kom pres yo nu için ame li yat edil di. Do ku ta nı sın dan son ra radyo te ra pi ve ke mo te ra pi te da vi si gö ren has ta nın sur ve yi sa de ce üç ay sür müş tür.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Ma lign fib röz his ti o si to ma; bel ağ rı sı; omur ga T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J M Me ed d S Sc ci i 2 20 01 11 1; ;3 31 1( (6 6) ): :1 15 57 70 0--3 3

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“…3 MFH of bo ne was first des cri bed as a se pa ra te en tity in 1972. 5 It is an un com mon tu mo r seen in ol der age gro ups.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Primary Malignant Fibrous Histiocytoma in Lumbar Vertebra: Case Report

Öksüz¹,

Deniz²,

Köseoğlu³

2011

Turkiye Klinikleri J Med Sci

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“…MFH with spine involvement is rare, but includes cases originating from the paravertebral tissue with secondary extension into the spinal canal, and metastases to the spine. 1,4,[8][9][10][12][13][14][15][18][19][20][21][22][23] Here we describe a case of MFH in a 75-year-old woman referred for treatment of a thoracic spine mass manifesting rapidly progressive weakness of the bilateral legs.…”

Section: Introductionmentioning

confidence: 99%

Malignant Fibrous Histiocytoma of the Thoracic Spine Manifesting as Rapidly Progressive Compressive Myelopathy -Case Report-

Ochiai

Kawano

Shimao

et al. 2009

Neurol. Med. Chir.(Tokyo)

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A 75-year-old woman presented with an extremely rare case of malignant fibrous histiocytoma (MFH) arising in the thoracic spine, causing compression fracture and manifesting as rapidly progressive compressive myelopathy resulting in progressive gait disturbance and weakness of the bilateral legs. Computed tomography and magnetic resonance imaging demonstrated a solid enhanced intravertebral mass destroying the vertebral bodies at the T7 and T8 levels. Maximum resection of the lesion was performed through wide laminectomy from T7 through T9, followed by vertebroplasty using calcium phosphate paste and posterior fixation with a spinal fixation system. Histological examination showed proliferation of pleomorphic spindle-shaped cells having large irregular nuclei with hyperchromasia with storiform pattern and collagenous stroma, consistent with a diagnosis of MFH. This case illustrates the possibility of rapid maximum decompression surgery from the posterolateral side if MFH manifests as progressive transverse myelopathy.

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