Malignant fibrous histiocytoma of the gallbladder: A case report

Kristofferson, Anders O.; Domellöf, L; Emdin, Stefan O.; Kullenberg, K

doi:10.1002/jso.2930230113

Cited by 9 publications

(2 citation statements)

References 19 publications

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“…High rates of incidence are indicated for In our investigative study, in line with the results of Brunschwig [42], Jaffe [43], and Rose [MI, primary sarcomas of the gallbladder represent a great rarity. Of the malignant nonepithelial gallbladder tumors, single malignant melanomas [20, [45][46][47], rhabdomyosarcomas [48], and malignant fibrous histiocytomas [49] are described, whereas one part of the sarcomas was not explained further histogenetically [20,47].…”

Section: Primary Localization and Pattern Of Growthmentioning

confidence: 99%

Carcinoma of the gallbladder: Autopsy findings in 287 cases and review of the literature

Sons¹,

Borchard²,

Joel³

1985

Journal of Surgical Oncology

126

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From 1950 to 1982, 287 patients with cancer of the gallbladder were autopsied. The ratio of men to women was 1:3.7. The average age of women was 70 years; that of men was 69.5 years. Most tumors (67.7%) had grown by diffuse infiltration and one-third (32.3%) were polypous-exophytic. Fundus and collum of the gallbladder showed an equal frequency (24%) of tumor localisation. The percentage of all gallbladder malignomas that were adenocarcinomas of various differentiation was 84.6, and 10.9% were anaplastic carcinomas, the rest consisted of squamous cell carcinomas (3.7%) and 0.8% sarcomas. Metastases were found in 265 cases (92.3%). Tumorous infiltration, lymph node metastases, and visceral metastases are discussed. A cholelithiasis was found in 78.4%. The results are compared with the literature.

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Section: Primary Localization and Pattern Of Growthmentioning

confidence: 99%

Carcinoma of the gallbladder: Autopsy findings in 287 cases and review of the literature

Sons¹,

Borchard²,

Joel³

1985

Journal of Surgical Oncology

126

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“…MPH is a soft tissue sarcoma of mesenchymal origin, and it can present as a primary gallbladder malignancy in rare cases. This localization was first described by Kristofferson et al 3 in 1983 and has been characterized by a uniformly fatal course.…”

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confidence: 73%

Malignant Fibrous Histiocytoma of the Gallbladder: Case Report and Review of the Literature

Gruttadauria

Doria

Minervini

et al. 2001

The American Surgeon

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Malignant fibrous histiocytoma is a soft tissue sarcoma of mesenchymal origin. It can rarely present as a primary gallbladder tumor with only five cases having been reported to date in the English literature. Here we report the sixth documented case of malignant fibrous histiocytoma of the gallbladder, and we review all other cases reported. The outcome of the visceral sarcomas is poor when compared with tumors arising from the soft tissues. The treatment of primary malignant fibrous histiocytomas of the gallbladder is surgery. However, tumor recurrence is the norm even if wide clean margins are obtained. In contrast to tumors arising from the extremities the role of adjuvant radiotherapy and chemotherapy is less clear in the case of retroperitoneal and visceral sarcomas. Our patient is still alive and free of disease 46 weeks after surgery. The fact that this is the longest survival reported to date underscores the dismal prognosis of this disease.

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