Malignant Fibrous Histiocytoma of the Spermatic Cord: The Role of Retroperitoneal Lymphadenectomy in Management

Sclama, Anthony O.; Berger, Bruce W.; Cherry, Joel M.; Young, John

doi:10.1016/s0022-5347(17)51316-6

Cited by 25 publications

(17 citation statements)

References 23 publications

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“…RPLND is required for those rare cases of tumors with retroperitoneal nodal metastasis identified on imaging studies [20,25], intermediate or high-grade malignant fibrous histiocytoma and fibrosarcoma [23,26] and according to the pathological specimen (e.g. if capsular invasion into the cord tissues is evident).…”

Section: Discussionmentioning

confidence: 99%

Spermatic Cord Sarcoma: Our Experience and Review of the Literature

et al. 2012

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Introduction: Spermatic cord tumors represent 4% of scrotal tumors. The most common neoplasms are lipomas. Spermatic cord sarcomas (SCS) of the genitourinary tract account for 2% of all urological tumors. Herein we presented our experience in the treatment of these tumors and a review of the literature. Patients and Methods: A review of the literature was performed using the Medline database with no restriction on language and date of published papers. The literature search used the following terms: epidemiology, surgery, chemotherapy, radiotherapy and spermatic cord sarcomas. Four cases treated from December 2009 to May 2010 are described. Results: All patients were treated with radical orchiectomy. The final pathological report showed different types of sarcomas. Two of the patients were treated with adjuvant chemotherapy. 12 months after surgery, 2/4 patients were alive without signs of relapse. Conclusion: SCS are very rare tumors with a poor prognosis. SCS’s prognostic factors have been identified in grading, size, depth of invasion and surgical margin status. Age and performance status of the patient are however very important. Lymphatic and hematogenous dissemination is uncommon. Surgery is the most important treatment both in the first approach and in local relapse. The role of adjuvant chemotherapy and radiation therapy is still debated.

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Section: Discussionmentioning

confidence: 99%

Spermatic Cord Sarcoma: Our Experience and Review of the Literature

et al. 2012

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“…Retroperitoneal lymph node dissection is advocated in cases with rhabdomyosarcoma, intermediate or high-grade MFH, and fibrosarcoma, on the basis of pattern of relapse and low probability of salvage of retroperitoneal recurrence (3,4,21) and according to the pathological specimen, if capsular invasion into the cord tissues is evident (4), or lymphadenopathy is evident in CT studies (17). In our series this procedure was performed in two patients with rhabdomyosarcoma, and in two patients with other histologies.…”

Section: Discussionmentioning

confidence: 99%

“…In adults, while radical orchiectomy is considered the procedure of choice for spermatic cord STS, retroperitoneal lymph node dissection, as well as adjuvant radiation therapy and chemotherapy remain controversial treatments (1)(2)(3)(4). The paucity of literature data makes treatment decisions more complicated.…”

Section: Original Articlementioning

confidence: 99%

Spermatic Cord Sarcoma in Adults

Merimsky

Terrier²,

Bonvalot³

et al. 1999

Acta Oncologica

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“…Some authors recommend postoperative radiotherapy in order to reduce the recurrence rate [6,7,11,15].…”

Section: Discussionmentioning

confidence: 99%

Malignant Fibrous Histiocytoma of the Epididymis

Ikinger

Westrich²,

Bersch³

et al. 1999

Urol Int

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A 54-year-old patient was found to have a painless ca. 1.5 cm diameter tumor in the region of the right epipidymis. The right testis was exposed from a scrotal incision. The final pathology surprisingly showed malignant fibrous histiocytoma (MFH) of the epipidymis and the patient subsequently underwent radical inguinal orchiectomy. Complete metastatic screening was normal. Postoperatively, 60 Gy external beam radiation was administered. At the least follow-up (6 years), there were no recurrences or metastases. MFH is an extremely rare, highly malignant connective tissue tumor, which may, occasionally, affect the male genital tract. There are no agreed treatment principles. The overall prognosis is poor.

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Malignant Fibrous Histiocytoma of the Spermatic Cord: The Role of Retroperitoneal Lymphadenectomy in Management

Cited by 25 publications

References 23 publications

Spermatic Cord Sarcoma: Our Experience and Review of the Literature

Spermatic Cord Sarcoma: Our Experience and Review of the Literature

Spermatic Cord Sarcoma in Adults

Malignant Fibrous Histiocytoma of the Epididymis

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