Malignant Detection of Breast Nodules On BIRADS-Based Ultrasound Images Margin, Orientation, And Posterior

Abstract

Breast cancer has the largest prevalence in the world in 2020, with 2,261,419 cases or 11.7%. It is also the leading cause of cancer death, accounting for 6.9% of all cancer deaths. Asia and Indonesia have the greatest prevalence and mortality rates. This is an urgent issue that must be addressed. Ultrasonography (USG) is advised for assessing the features of breast nodules. Breast nodules on ultrasound pictures are interpreted using the Breast Imaging, Reporting, and Data System (BIRADS) category, which has five features. Yet, the probability of a False Positive Result (FPR) on ultrasound imaging is relatively high. Computer Aided Diagnosis (CAD) was created to reduce FPR. However, CAD research based on many BIRADS traits is currently margined. As a result, based on three BIRADS characteristics, namely the margin, posterior, and orientation aspects, this study aims to proposed the methode for diagnosing breast nodule malignancy. The proposed method consists of 4 stages, namely, pre-processing, automatic segmentation, features extraction, and classification. Pre-processing adaptive median filter maximum window size is 11 pixels, linear histogram normalizing, and Reduction Anisotropic Diffusion (SRAD) filter were used to construct the method. The neutrosophic watershed method was used in the suggested automatic segmentation. Based on the nodule's margin, orientation, and posterior, 10 features were proposed: nodule width, gradient, slenderness, margin sharpness, shadow indicators, skewness, energy, entropy, dispersion, and solidity. MLP is a classification approach. The test used 94 nodule pictures and yielded an accuracy of 88.30%, a sensitivity of 82.35%, a specificity of 91.67%, a Kappa of 0.7449, and an AUC of 0.865. As a result, it is feasible to conclude that the proposed method is capable of detecting malignancy in breast nodules in ultrasound images. To make the proposed method more reliable in the future, automatic RoI can be developed.