Malignancy in Renal Transplantation

De novo papillary carcinoma in a renal allograft: the pros and cons of immunosuppression

“…We found no studies relating steroid use and the risk of malignancy in solid organ transplantation, this is likely to be due to the fact that steroids are used in the majority of immunosuppression protocols. Immunosuppressive drugs might increase the post-transplant risk of malignancy by impairing immunosurveillance [28] and facilitating the action of oncogenic viruses [29]. Indeed, some infective pathogens, such as Epstein-Barr virus (EBV), human papillomaviruses (HPV) and herpes virus 8, have also been associated with increased risk of malignancy.…”

Two papillary renal cell carcinomas of different origin following renal transplantation (Case report)

“…The overall prevalence of post-transplantation malignancy is significantly increased following renal transplantation (2,3). A total of 5% of all malignancies are kidney tumors; twice the amount of that in the general population (4).…”

Letter to the editor: giant angiomyxoid tumor in a renal allograft

“…There is increased incidence of neoplasia in transplant patients compared with the general population; a dominant predictor of this is the intensity and duration of immunosuppression [2]. In nontransplant patients who receive immunosuppression for other conditions, they are equally likely to develop tumors [2,3].…”

“…In nontransplant patients who receive immunosuppression for other conditions, they are equally likely to develop tumors [2,3].…”