Malignancy in a Massive Localized Fibrous Tumour of Pleura

Abstract

Localized fibrous tumour of pleura is a rare condition. Most follow a benign course and are an incidental finding during routine chest X‐ray. A small proportion of these amours are malignant and have characteristic clinical and histopathological features. This case report is of a 65 year old woman who presented with respiratory symptoms and polyarthropathy, and had a subsequent resection of a massive pleural tumour with features suggestive of malignancy.

CT features of solitary fibrous tumour of the pleura: experience in 26 patients

“…It derives from the submesothelial connective tissue [2,3] and is not associated with exposure to asbestos fibres or tobacco smoking [4][5][6]. Over 50% of patients are asymptomatic at presentation, and the lesion is usually discovered in-…”

“…Deriva dal connettivo sottomesoteliale [2,3] e non si associa con l'esposizione alle fibre d'asbesto ed al fumo di sigaretta [4][5][6]. Oltre il 50% dei pazienti è asintomatico al momento della diagnosi e la lesione è riscontrata in cidentally on chest radiographs performed for other reasons [1,2,5,7,8].…”

Solitary fibrous tumours of the pleura

“…The majority of lesions behave in a benign fashion (88%), but approximately 12% of patients die of extensive intrathoracic tumour growth or an unresectable recurrence [13]. Malignant tumours may metastasize, and the local recurrences are more common in cases of malignant lesions than in benign lesions [99][100][101].…”

Two-stage Surgical Treatment of a Giant Solitary Fibrous Tumor Occupying the Thoracic Cavity

“…It is more probable that SFTs >8 cm will originate from the parietal pleura and to have a vascular pedicle [2]. A solitary pedicle attaches about 50% of SFTs with the pleura [3], and up to 47% are encapsulated by a membrane containing a vascular network [3,5]. Notably, a highly vascularized pedicle attaches SFTs in 38% to 46% of patients to the pleura [3], and this is more likely if the tumor is large.…”