Male patients with unilateral breast symptoms: an optimal imaging approach

Yoon, Bo Sung; Chae, Eun Young; Hee, Joo; Shin, Hee Jung; Choi, Woo Jung; Kim, Hak Hee

doi:10.1007/s00330-020-06828-3

Cited by 7 publications

(2 citation statements)

References 28 publications

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“…In our cohort, the AUC (0.904), sensitivity (96.2%), and the accuracy (76.7%) of group III were the highest, while the speci city (75.9%) of group I was the highest in the three groups. Our ndings were similar to those of Huang et al (12), but were somewhat lower AUCs than those reported by Yoon et al (21). whose sensitivity was 100%, speci city was 92.2%, and accuracy was 94.0%.…”

Section: Discussionsupporting

confidence: 90%

Use of US BIRADS for the Differentiation of Male Breast Masses and Interobserver Agreement Assessment

Wang,

Dang,

Wang

et al. 2024

Preprint

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Purpose To investigate the efficiency of Breast Imaging Reporting and Data System (BIRADS) proposed by the American College of Radiology for male breast lesions and to evaluate assess inter-observer agreement. Methods Six breast radiologists were divided into three groups to retrospectively analyze 90 male breast nodules by BIRADS classifications. The area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and accuracy were calculated for comparative analysis. Interobserver agreement was assessed. Results The group II showed the higher specificity (75.9%) than other two groups while the group III showed the best AUC, sensitivity and accuracy, which were 0.904, 97.2%, 62.9% and 76.7%, respectively. Besides, the whole of three groups expressed excellent ICC on 2(0.934) category and good on BIRADS 3 (0.677) category. The ICC of 4a (0.379) was expressed as poor level. The categories of 4b (0.483) ,4c (0.521) and5(0.491) was expressed as fair level. Only group I had significant difference with the group III in diagnostic effectiveness of the same systems among three groups. Conclusions Male sex did not have a large impact on the diagnosis of BIRADS and use of US BIRADS lexicon shows excellent or good levels of concordance for mass characterizations. But a lower concordance respect to BIRADS classifications in BIRADS 4 categories.

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Section: Discussionsupporting

confidence: 90%

Use of US BIRADS for the Differentiation of Male Breast Masses and Interobserver Agreement Assessment

Wang,

Dang,

Wang

et al. 2024

Preprint

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“…Male patients presenting with breast symptoms such as breast enlargement, nipple discharge, breast pain, and palpable lump are usually concerned about the underlying cause and whether or not the symptoms are a manifestation of breast cancer. The most common cause of breast symptoms in male patients is gynecomastia, especially in younger patients, as MBC has a later onset on average in comparison to gynecomastia, which can present at any age [ 10 ]. Detection of MBC often occurs at a later stage compared to female breast cancer due to the rarity of breast cancer in men as well as a lower index of suspicion at initial presentation; therefore, more advanced features such as larger tumor size, the involvement of lymph nodes, and metastases at the time of diagnosis are more common in male versus female breast cancer [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of Male Breast Cancer Patient with CHEK2*1100delC Mutation

Nguyen¹,

Tavana²,

Rios³

et al. 2020

Cureus

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Male breast cancer (MBC) is a rare disease that accounts for less than one percent of all breast cancers. The association between BRCA1 and BRCA2 mutations and MBC has been well-established; recent data suggest that CHEK2 1100delC heterozygosity is also associated with an increased risk of MBC. Herein, we present the case of a 47-year-old male who was initially diagnosed with bilateral symmetric gynecomastia on a diagnostic mammogram performed for right breast palpable lump. Sixteen months after his diagnosis of gynecomastia, he presented with enlarging right breast palpable lumps and underwent a diagnostic mammogram and breast ultrasound. Ultrasound-guided biopsies were performed on the right breast mass and axillary lymphadenopathy. Pathology revealed right breast invasive ductal carcinoma (IDC) and right axillary metastatic lymphadenopathy. Subsequent genetic testing found CHEK2*1100delC mutation. This case report focuses on the presentation, diagnosis, and management of breast cancer, as well as long-term cancer screening in the setting of CHEK2 mutation in a relatively young male patient.

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Male Breast Reduction Surgery

Cohen-Zarade

2024

Imaging of Plastic Surgery of the Breast and Other Implants

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Male patients with unilateral breast symptoms: an optimal imaging approach

Cited by 7 publications

References 28 publications

Use of US BIRADS for the Differentiation of Male Breast Masses and Interobserver Agreement Assessment

Use of US BIRADS for the Differentiation of Male Breast Masses and Interobserver Agreement Assessment

A Case of Male Breast Cancer Patient with CHEK2*1100delC Mutation

Male Breast Reduction Surgery

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