Male partner sexual abstinence less than 2 or greater than 7 days is not associated with increased aneuploidy rate

Abstract

was a significant decline in initial sperm count (p < 0.001), sperm motility (p < 0.001), total count (p < 0.001) and total motile count (p < 0.001) during the period 2003-2013. There was no significant change in semen volume (p ¼ 0.2). Following cryopreservation, the mean post-thaw motility significantly (p < 0.001) decreased with time. There was a significant decline in age (p trend ¼ 0.003) and alcohol use (p trend ¼ 0.005), as well as an increase in college GPA (p trend ¼ 0.02). However, BMI (p trend ¼ 0.73) educational attainment (p trend ¼ 0.2), race/ethnicity (p trend ¼ 0.53), and lifestyle habits (weekly exercise, p trend ¼ 0.21; smokers p trend ¼ 0.99; marital status, p trend ¼ 0.85) remained constant over the period of study.CONCLUSIONS: There has been a decline in semen quality among young men presenting for sperm donation during the past 11 years. Uniform technicians and techniques over the study period make measurement bias unlikely. Subject characteristics also remained constant during the study period. The decrease in sperm count and motility following cryopreservation suggests that the sperm were not as vital since cryosurvival appears to be compromised over the ten-year poor of time. This report demonstrates a decline in sperm count in a young adult male population. Although absolute values did not decline into the abnormal or sub fertile range, it may be prudent for men to consider sperm cryopreservation if fertility is being delayed until later years/advanced age.

Effect of the sexual abstinence period recommended by the World Health Organization on clinical outcomes of fresh embryo transfer cycles with normal ovarian response after intracytoplasmic sperm injection

“…In a recent study, Gingold et al. () reported that SAP beyond the range recommended by the WHO was not associated with an increased aneuploidy rate. Additionally, in our previous study, we found no significant differences between 2–4 and 5–7 days of SAP on the rates of fertilisation, top‐quality embryos on day 3 and pregnancy outcomes in fresh ET after ICSI (Lee et al., ).…”