Male hormone in the treatment of the menopause

Walter, Robert I.

doi:10.1016/0002-9378(53)90574-2

Cited by 9 publications

(2 citation statements)

References 24 publications

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“…They found that this combination therapy was more effective than either treatment alone and that 72% of patients preferred this treatment. Although many studies did find androgens to be helpful either alone or in conjunction with estrogen, Walter recommended against androgen therapy as only 27% of his patients benefitted and 32% of the 52 patients experienced some type of masculinization phenomena [55].…”

Section: Androgen Therapy Of Menopausementioning

confidence: 99%

Testosterone Therapy in Women with Gynecological and Sexual Disorders: A Triumph of Clinical Endocrinology from 1938 to 2008

Traish

Feeley

Guay

2009

The Journal of Sexual Medicine

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Introduction Although the term “medicalization” has been used by some to describe contemporary testosterone use in women with sexual disorders and testosterone deficiency syndrome, testosterone therapy for women with various gynecological and sexual disorders has been practiced since the late 1930s. Aim The study aimed to perform a historical review of testosterone use in women with sexual and gynecological disorders. This review is necessary to bridge important knowledge gaps in the clinical use of testosterone in women with sexual health concerns and to provoke new thoughts and understanding of the multidisciplinary role of testosterone in women’s overall health. Methods Review of medical literature on androgen therapy in women was carried out from 1938 through 2008. Results Approximately 70 years ago, clinicians from various disciplines relied on personal experience and clinical observations for outcome assessment of testosterone therapy in women. These early reports on testosterone use in women with sexual medical problems served as a foundation for the development of contemporary approaches and subsequent testosterone treatment regimens. Testosterone use was reported for sexual dysfunction, abnormal uterine bleeding, dysmenorrhea, menopausal symptoms, chronic mastitis and lactation, and benign and malignant tumors of the breast, uterus, and ovaries. Conclusions Health-care professionals engaged in the management of women’s health issues have observed the benefits of androgen therapy throughout much of the 20th century. Despite this clinical use of testosterone in women for more than seven decades, contemporary testosterone therapy in women is hotly debated, misunderstood, and often misrepresented in the medical community.

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Section: Androgen Therapy Of Menopausementioning

confidence: 99%

Testosterone Therapy in Women with Gynecological and Sexual Disorders: A Triumph of Clinical Endocrinology from 1938 to 2008

Traish

Feeley

Guay

2009

The Journal of Sexual Medicine

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“…X-ray therapy aimed at decreasing the activity of the pituitary was advocated: one study claimed that 80% of patients reported relief of menopausal symptoms.F Testosterone was also used for the purpose of inhibiting the pituitary and in the late 1930s, as concern grew about the possible carcinogenic effects of oestrogen, it was suggested that vitamin E might be a useful alternative to hormonal preparations. 23,24 After the Second World War, hormonal explanations for the menopause receded in popularity, and psychoanalytic models were increasingly deployed in their place. The publication in 1945 of Helene Deutsch's influential work on female psychosexual development took place in the babyboom atmosphere that characterised the post-war era, prompting a reassessment of the menopause as a psychological response to the "empty womb/empty nest'tcrisis.l As a key text on psychosomatic gynaecology stated in 1951, "it would appear that oestrogen deficiency per se is of minor importance in the development of the menopausal syndrome; that it is but one among numerous somatic, social, domestic and personality factors which precipitate emotional disturbances".…”

Section: The Beginnings Of Hormone Replacement Therapymentioning

confidence: 99%

Medicine, Age and Gender: The Menopause in History

Moscucci¹

1999

British Menopause Society Journal

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Attitudes to the menopause in Western Europe and America have been. shaped by changing ideas about age and gender. No concept of a biological process specific to the human female and due to the cessation of menstruation existed before 1821: doctors did not differentiate between the male and female ageing process, and the word "climacteric" was used to indicate the transition from one epoch of human life to the next, regardless of gender. In the 19th century, however, sharp boundaries were drawn between male and female, and reproduction became the defining quality of femininity. The construction of womanhood that emerged at this time served to focus the attention on the menopause as a crisis that had to be negotiated. During the Victorian period leeching, cold baths and sedatives were prescribed for the menopause, and the importance of hygiene and moral management was emphasised. By the early 20th century, ovarian extracts were also employed in clinical practice, although their efficacy was often disputed. The development of reproductive endocrinology in the 1920s led to the isolation of oestrogen, and hormonal preparations were soon developed for the treatment of menopausal symptoms. Hormonal therapy receded in importance after the Second World War as psychoanalytic theory briefly replaced the hormonal paradigm as a tool for understanding the menopausal syndrome. In the 1960s, however, the psychoanalytic model was once again displaced by the growing importance of endocrinological explanations. Both old and new notions of gender and age have affected medical and lay perceptions of the menopause in the 20th century: in particular the cult of youth that emerged in the early part of this century has dominated images of ageing and the menopause, influencing the messages women receive about the mid-life period.

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Klimakterium und innere Medizin

Hoff¹

1959

Zweiunddreissigste Versammlung Abgehalten Zu Frankfurt a.M. Vom 16. Bis 20. September 1958

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Male hormone in the treatment of the menopause

Cited by 9 publications

References 24 publications

Testosterone Therapy in Women with Gynecological and Sexual Disorders: A Triumph of Clinical Endocrinology from 1938 to 2008

Testosterone Therapy in Women with Gynecological and Sexual Disorders: A Triumph of Clinical Endocrinology from 1938 to 2008

Medicine, Age and Gender: The Menopause in History

Klimakterium und innere Medizin

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