Male-female differences in the number of reported incident dengue fever cases in six Asian countries

Anker, Martha; Arima, Yuzo

doi:10.5365/wpsar.2011.2.1.002

Cited by 136 publications

(146 citation statements)

References 13 publications

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“…The male predominance has also been reported in several other studies [6]. The mean age of patients in our study was 32.4 years which is similar to other studies where higher age groups were observed of developing symptomatic disease than younger groups [7][8][9] and contradictory to the study by Raut and Patil where they revealed children <10 years were affected more [10].…”

Section: Discussionsupporting

confidence: 86%

A Study of Multiorgan Dysfunction in Patients With Dengue and Its Clinico- Haematological Correlation With Severity.

Nayak

Behera

Swain

et al. 2017

Asian J Pharm Clin Res

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Objective: The aim was to study of multiorgan dysfunction in patients with dengue and to correlate the severity and clinical outcome with different hematological parameters.Methods: All suspected cases of dengue admitted to medicine department within 1 year were evaluated and classified as dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Results:Out of 150 cases, 108 cases were classified as DF, 31 cases as DHF and 11 cases as DSS. Liver involvement was seen in 97.33% of cases. Jaundice was observed in 10 cases (6.6%), abnormal aspartate transaminase in 146 (97.33%) cases, and abnormal alanine transaminase in 126 (84%) cases. Bleeding manifestations was reported in 61 patients (40.6%). The presence of gastrointestinal bleeding in 17 patients (11.3%) was related to severe disease. Thrombocytopenia was present in 25% of DF cases, and in all cases of DHF and DS. Among these, prothrombin time (PT) was prolonged in 10 cases and activated partial thromboplastin time (aPTT) in 47 patients. Serum fibrinogen was low in 28.57% of patients. Multiorgan dysfunction was observed in the form of simultaneous hepatic and renal dysfunction in 3.33% of cases, hepatic and central nervous system dysfunction in 2.66% of cases, hepatic and cardiac dysfunction in 2% of cases, and all the organ system dysfunction in 0.67% of cases. Conclusion:The extent of increase of liver enzymes, PT, aPTT and fall of serum fibrinogen, and degree of thrombocytopenia correlated with disease severity. Acute renal failure, encephalitis, and myocarditis are manifestations of severe form of dengue. Major organ involvement may occur in simple DF also.

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Section: Discussionsupporting

confidence: 86%

A Study of Multiorgan Dysfunction in Patients With Dengue and Its Clinico- Haematological Correlation With Severity.

Nayak

Behera

Swain

et al. 2017

Asian J Pharm Clin Res

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“…7 In the present study, male predominance (62%) was noted which is in comparable with the previous study conducted in six asian countries by anker et al In addition, our study also showed that the bleeding tendencies are common in females (57%) as compared to males. 8 In our study we also found that fever (92%) and vomiting (44%) are the most common presenting illness. Among all bleeding manifestations, melena (48%), petechial hemorrhages (28%) are common .…”

Section: Bleeding Signs Discussionsupporting

confidence: 67%

Comparison of Platelet Indices with Platelet Count to Predict Bleeding Tendency in Seropositive Dengue Cases

Ramamoorthy¹

2017

jmscr

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“…[5] Three independent studies from epidemics in India done by Agarwal et al, Ray et al, and Wali et al, also found nearly twice the number of male patients infected with dengue compared to females, M:F being 1.9:1, 1:0.57, and 2.5:1, respectively.…”

Section: Discussionmentioning

confidence: 92%

IUse of Mean platelet Volume as an initial diagnostic marker in evaluation of dengue fever

Afsar

Afroze

Humaira

et al. 2017

APALM

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Background: Dengue fever is the most rapidly spreading mosquito-borne viral disease. Four main characteristic manifestations of dengue illness are (i) continuous high fever lasting 2-7 days; (ii) haemorrhagic tendency as shown by a positive tourniquet test, petechiae or epistaxis; (iii) thrombocytopoenia (platelet count <100×109/l); and (iv) evidence of plasma leakage manifested by haemoconcentration (an increase in haematocrit 20% above average for age, sex and population), pleural effusion and ascites, etc. Recently, novel platelet indices such as MPV, PDW, and P-LCR have been investigated as prospective platelet activation markers .Platelet volume, a marker of platelet function and activity is measured as mean platelet volume (MPV) by hematology analyzer. Method:The study was done with the aim to assess whether mean platelet volume has any diagnostic importance in the initial evaluation of dengue fever . 45 adult patients were diagnosed with Dengue NS1 antigen positivity and underwent routine complete blood counts on automated hematology analyser HORIBA Pentra ES60.Result: A total of 76 cases ranging from 6 months to 50 years of age were reported as antigenically positive for dengue indicating acute infection, out of which 45 were adults ranging from 12 to 50 years of age. 34 were male and 11 were female. Infants and children below 12 years of age were not included in this study. 55 controls were studied which included 31 males and 24 females. The mean platelet volume was found to be significantly higher in dengue cases when compared to controls. MPV was also noted to be significantly higher in patients with platelet count below the normal biological reference range of 1.5 lakhs ,when compared to dengue patients with normal platelet counts. Conclusion:To conclude, high MPV indicates platelet activation and may be used as an initial marker to suspect dengue fever in a case of thrombocytopenia.

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Male-female differences in the number of reported incident dengue fever cases in six Asian countries

Cited by 136 publications

References 13 publications

A Study of Multiorgan Dysfunction in Patients With Dengue and Its Clinico- Haematological Correlation With Severity.

A Study of Multiorgan Dysfunction in Patients With Dengue and Its Clinico- Haematological Correlation With Severity.

Comparison of Platelet Indices with Platelet Count to Predict Bleeding Tendency in Seropositive Dengue Cases

IUse of Mean platelet Volume as an initial diagnostic marker in evaluation of dengue fever

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