2000
DOI: 10.1097/00002030-200010200-00019
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Male circumcision and HIV acquisition and transmission: cohort studies in Rakai, Uganda

Abstract: Prepubertal circumcision may reduce male HIV acquisition in a general population, but the protective effects are confounded by cultural and behavioral factors in Muslims. In discordant couples, circumcision reduces HIV acquisition and transmission. The assessment of circumcision for HIV prevention is complex and requires randomized trials.

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Cited by 216 publications
(164 citation statements)
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“…In another study in the same community researchers reported in 1999 that the HIV incidence rates were significantly lower in Muslims compared to non-Muslims [26]. Researchers in another district called Rakai also reported a lower incidence of HIV infections among Muslims compared to non-Muslims [27]. In the 2004-05 Uganda HIV/AIDS sero-behavioral survey, the HIV prevalence was also lower among Muslims compared to non-Muslims [19].…”
Section: Discussionmentioning
confidence: 99%
“…In another study in the same community researchers reported in 1999 that the HIV incidence rates were significantly lower in Muslims compared to non-Muslims [26]. Researchers in another district called Rakai also reported a lower incidence of HIV infections among Muslims compared to non-Muslims [27]. In the 2004-05 Uganda HIV/AIDS sero-behavioral survey, the HIV prevalence was also lower among Muslims compared to non-Muslims [19].…”
Section: Discussionmentioning
confidence: 99%
“…Even though other modes of transmission have taken over in the west, heterosexual transmission to the male may be reduced by lowering foreskin prevalence among men, many of whom will visit countries in which HIV abounds. Moreover, in some, 21,22 but not other, 12 studies the effectiveness of circumcision in AIDS risk reduction was greater when performed prior to puberty or sexual debut.…”
Section: Hiv/aidsmentioning
confidence: 97%
“…The Rakai study in urban Uganda (Quinn et al 2000;Gray et al 2000) is the only one where a clear pattern is found: but this only in as small a "population" as 50 men. The Rakai researchers themselves do not, however, promote male circumcision in their conclusions (Quinn et al 2000:928), but maintain that the issue is too complicated-for example by social factors-for any recommendations.…”
Section: Scientific Uncertaintymentioning
confidence: 99%
“…During the 1990s the research on male circumcision takes regional and cultural differences in African societies more seriously, and detailed studies within local communities are conducted (Urassa et al 1997;Quinn et al 2000;Gray et al 2000;Oliver et al 2000). The Rakai study in urban Uganda (Quinn et al 2000;Gray et al 2000) is the only one where a clear pattern is found: but this only in as small a "population" as 50 men.…”
Section: Scientific Uncertaintymentioning
confidence: 99%