Male Breast Cancer Associated with Paget’s Disease: A Case Report

İkizceli, Türkan; Gülşen, Gökçe; Insan, Aykut; Savas, Yildiray; Erözgen, Fazilet

doi:10.4274/haseki.3967

Cited by 1 publication

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References 8 publications

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“…Paget’s disease is a rare disease and constitutes 1% of breast cancers. It is an eczematous skin disease, usually associated with an underlying breast cancer ( 6 ). Considering that male breast cancers constitute 1% of all breast cancers, the incidence of Paget’s disease in male breast cancer is very low.…”

Section: Discussionmentioning

confidence: 99%

Male breast cancer: clinicopathological, immunohistochemical and radiological study

Hasbay

Bolat²,

Aytaç³

et al. 2020

TJPATH

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Objective: To evaluate the pathological and radiological features, immunohistochemical profile and treatment methods of primary male breast carcinoma cases diagnosed at our center. Material and Method: The pathology archive between 2006 and 2019 was reviewed and the data of 27 male patients diagnosed as primary breast cancer were retrospectively evaluated. Results: The age of the patients ranged between 40-86 years. The left breast was involved in 17 patients. The mean tumor diameter was 2.35 ± 1.09 cm. Of the 27 cases, 8 were dead and 19 were alive. The mean follow-up duration was 37.45 ± 24.84 months. The mean estimated life expectancy was 65±14.7 months. The most common complaint was a swelling in the breast. The time interval between the onset of complaints and admittance to hospital ranged from three months to two years. The most common histopathological diagnosis was invasive carcinoma-no special type. The most common surgical procedure was mastectomy with lymph node dissection. Nine patients had metastatic lymph nodes. In terms of the hormone profiles, 24 were Estrogen receptor positive, 21 were Progesterone receptor positive and six were Her2/neu positive. Three patients had triple-negative tumors. Conclusion: Male breast carcinoma is a rare disease but its frequency has been increasing recently. As breast cancer is more commonly attributed to women, the diagnosis is usually delayed until later stages in males. Public awareness should therefore be increased and breast cancer should be considered in the differential diagnosis especially in the presence of breast swelling and complaints related to the breast skin so that the appropriate biopsy can be obtained without delay.

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Section: Discussionmentioning

confidence: 99%