Male Breast Cancer: A Rare Entity

Abstract

Male breast carcinoma is a rare malignancy (<1% of all breast carcinomas, 0.2% of all male malignancies). Its common histopathological type is infiltrating carcinoma, not otherwise specified. Three male patients aged 56 (stage –IIIB), 64 (T4bN0M0) and 78 (T2N0MO) years presented with a breast lump within a year. Their hematological and biochemical parameters were within normal limits. Two of them had palpable regional lymph nodes. Male breast carcinoma occurs in older males as in our cases. Two cases showed infiltrating ductal carcinoma, not otherwise specified on histopathological evaluation, and one showed special type with apocrine differentiation. Their two-year follow-up was uneventful after modified radical mastectomy and chemotherapy. Male breast carcinoma is associated with risk factors different from and overlapping with female breast carcinoma. Male breast carcinoma differs from female breast carcinoma on clinical presentation, biological behaviour and prognosis.

Aggressive Male Breast Cancer—Clinical and Therapeutic Aspects Correlated with the Histopathological Examination: A Case Report and Literature Review

“…Most of the cases in our review had as their main symptom the presence of a tumor mass in the breast or axilla. Eleven cases presented tumors larger than 2 cm in size [14][15][16][17][20][21][22][23][24][25]27], while four cases had smaller sizes [19,21,26].…”

“…All patients underwent biopsy for diagnostic purposes, either with a core needle in five cases [14][15][16]18,22], fine-needle aspiration in four cases [23][24][25]27], or excisional biopsy in seven cases [17,[19][20][21]26]. Given that MBC is rare and there are not enough surgeons specialized in breast surgery in our country, there is a lack of experience in the management and early diagnosis of this type of cancer.…”