Male Breast Cancer: a 24 Year Experience of a Tertiary Care Hospital in Pakistan

Abstract

States has shown a significant increase in the incidence of MBC whereas a steady low rate has been observed in European studies. (Kaushik et al., 2014) There is still a paucity of randomized controlled trials and treatment for MBC is based on treatment for FBC.The general variation of MBC across the globe is similar to FBC with higher rates in North America and Europe and lower rates in Asia. (Chikaraddi et al., 2012;Kaushik et al., 2014) Materials and MethodsThis retrospective review was carried out at The Aga Khan University Hospital (AKUH) in Karachi, Pakistan. Approval was obtained from the ethics committee at AKUH. Files with ICD code 175 (Malignant neoplasm of male breast) were retrieved from patient medical records. A total of 19 patients with MBC were seen at our institute between January 1986 and December 2009. One patient with missing records was excluded from the study. Data from 18 files were reviewed and analyzed.The variables studied were age at diagnosis, comorbid conditions, presenting signs and symptoms (breast lump, erythema, nipple discharge and axillary lymphadenopathy), family history of breast cancer, smoking history, diagnostic modality, histopathology including hormonal work up, TNM staging, treatment

Male Breast Cancer: The Three Decades' Experience of a Tertiary Care Hospital in a Lower-Middle Income Country

“…2019-0391-2980). This study included 19 cases of MBC reported by Jamy et al from the same study institution in 2009 [ 11 ]. Data on demographics, clinicopathological features, and treatment modalities of all MBC patients were retrieved from the institution’s breast cancer database.…”

Clinicopathological characteristics of male breast lesion: An experience in a regional cancer center, Odisha

“…[4] However, literature has shown that exposure to estrogen can cause terminal lobules to develop carcinoma in the male breast. [28] In our study series, infiltrating ductal carcinoma-NOS type was the only malignant type. The same histological type was also found to common by others such as Fentiman et al, [9] in 2006, and Chikaraddi et al, [2] in 2012.…”

A case of male breast carcinoma

“…Breast carcinoma in men is rare which most often occurs at or after the age of 60 years. The cause of MBC (male breast carcinoma) remains unclear, however several risk factors were identified such as age of patient, genetic predisposition, anatomic factors and hormone metabolism abnormalities related to elevated estrogen or prolactin levels [1].…”