Male accessory breast cancer successfully treated with endocrine therapy: A case report

Abstract

Abstract. Male accessory breast cancer is an extremely rare tumor. Several risk factors have been identified, including genetic and hormonal abnormalities. Accessory breast carcinoma usually occurs under the axilla or in the inguinal region. Clinical diagnosis is frequently delayed due to the general lack of awareness among physicians and patients. In the present study, the case of a 63-year-old male patient who was diagnosed with accessory breast cancer at a local advanced stage was reported. However, the patient was successfully treated with endocrine therapy.

Successful treatment of accessory breast cancer with endocrine therapy

“…In the Chinese Hospital Knowledge Database from 1975 to 2015, there were two separate case reports of male accessory breast cancer (Gou, 1987;Liu and Wang, 2014), and 20 cases altogether with female patients in the retrospective analyses. Seven case reports in the PubMed literature were in English, of which one case was American (Camisa, 1980), three cases were Chinese (Lin and Wang, 2012;Gao et al, 2014;Bi et al, 2015), and three cases were Japanese (Takeyama et al, 2010;Yamamura et al, 2012;Yoshida et al, 2012). Camisa (1980) reported on an elderly man with accessory breast tissue occurring on the posterior portion of his left thigh.…”

“…Accessory breast carcinoma in males generally presents a poorer prognosis than that in females because the diagnosis tends to be delayed. Bi et al (2015) reported a 56-year-old Chinese male diagnosed with right accessory breast carcinoma (PT1N1M0) who underwent four surgical excisions of a primary ectopic breast carcinoma and developed local lymph node and opposite supraclavicular lymph node metastasis. Ultimately, the patient developed pulmonary and bone metastasis.…”

“…Accessory breasts develop from normal undegraded breasts at an occurrence rate of 2%-6% (Gutermuth et al, 2006). Cancer of accessory breasts is a rare form of breast cancer that usually occurs at an incidence rate of 0.2%-0.6%, usually in the axilla or inguinal region (Bi et al, 2015). Because accessory breast cancer in men, especially the elderly, is extremely rare, missed and erroneous diagnoses often occur, which result in higher instances of metastasis at an early stage and poor prognosis.…”

Male axillary accessory breast cancer

“…[ 3 ] Although glandular diseases can also develop in accessory mammary glands, cases of malignant tumors occurring in the accessory mammary glands are extremely rare, especially in male patients. [ 4 ] Therefore, clinicians are short of clinical experience of diagnosis and treatment for male accessory breast cancer, so that the aim of this article is to help clinicians better understand this type of disease.…”

Male breast cancer

“…As noted by Bi et al ., “clinical diagnosis is frequently delayed due to the general lack of awareness among physicians and patients. [ 2 ]” The basic suggestion for any suspected case is to “proceed directly to surgery as their initial diagnostic test. [ 3 ]” Volpe et al .…”