Malaria Parasitaemia Association with ABO Blood Types among Students of a Private University in Western Delta, Nigeria

Otajevwo, F. D.

doi:10.9734/ijtdh/2014/8479

Cited by 6 publications

(10 citation statements)

References 37 publications

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“…When comparing our findings with previously done studies (Table 11), we found that this was in concordance with 11 studies where O was the most affected blood group and in discordance with 4 other studies that had B as the most affected blood group, which in our case was the 2nd most affected. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] The distribution of blood groups in malaria infected patients, as obtained in our study, is actually in concordance with the normal ABO blood group distribution amongst the normal Indian population. According to a multicentric study conducted by Agarwal et al (2014), the most predominant blood group in India, overall, is "O" followed by "B", "A" and then "AB".…”

Section: Discussionsupporting

confidence: 73%

A Study on The Prevalence of ABO Blood Groups in Malaria Infection

Nair

2018

APALM

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Objectives: To analyse the distribution of blood groups in malaria positive patients in and around the city of Mangalore. Materials and Methods: This study was conducted from January 2015-December 2015. The study group consisted of malaria positive patients diagnosed by MPFT or MP Smear. Blood grouping, complete blood counts and peripheral smear examinations were done in these patients. Results: During the 1 year period of our study, there were 278 malaria positive patients. Of the 278 malaria positive cases, 262 (94.24%) cases were P.vivax, 2 (0.72%) were P.falciparum& 14 (5.04%) were mixed infections. The vast majority of the patients were male (83.5%) and the largest number of cases were seen in the 20-29 age group (39.9%). The most common peripheral smear finding was thrombocytopenia. 256 (92.1%) of the patients were Rh positive and only 22 (7.9%) of cases were Rh negative. The most common ABO blood group seen was O in 38.13% followed by B in 28.78%. A blood group had 26.6% and AB had only 6.83%. Overall, the most common of the 8 ABO-Rh groups seen was O positive (35.6%) followed by B positive (26.3%). Conclusions: In our study, malaria is found to be more prevalent in males, the most common species is P.vivax and most common age group is 20-29yrs. The most common haematological abnormality seen was thrombocytopenia and overall, malaria is seen to occur most in the O positive blood group which is in concordance with most other studies.

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Section: Discussionsupporting

confidence: 73%

A Study on The Prevalence of ABO Blood Groups in Malaria Infection

Nair

2018

APALM

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“…This is because transfusion of compatible blood groups is useful in clinical studies, population genetic studies, researching population migration patterns and resolving certain medicolegal issues especially relating to disputed paternity cases [54]. Rhesus grouping is based on the presence or absence of the D antigen on red blood cells [10,55].…”

Section: Discussionmentioning

confidence: 99%

“…ABO blood types as well as rhesus blood types have attracted enormous attention regarding their association with genetic and infectious diseases [55]. Previous studies on patients of cancer and tumor [67], heart disease [58], parasitic and viral infections [22] indicated associations of ABO and rhesus blood groups.…”

Section: Discussionmentioning

confidence: 99%

Abo Blood Variants of Selected Babcock University Students and Their Link with Malaria Parasitaemia

Dafinone¹

2018

PLM

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Five milliliters (5ml) of venous whole blood was collected from one hundred and eighty three students made up of 93(50.8%) male and 90(49.2%) female students of Babcock University, Ilishan Remo randomly selected across various Departments. Whole blood samples were dispensed into sequestrinized (EDTA anticoagulated) blood containers, properly mixed and labeled. Malaria Plasmodium falciparum parasite screening was done semi-quantitatively by Field stain A and B staining. ABO blood phenotyping was carried out with monoclonal Antisera A, B and D. A total of 169 (92.3%) and 14(7.7%) students were rhesus positive and negative respectively of which 92(54.4%) and 77(45.6%) samples were rhesus positive male and female students respectively and of which 1(7.1%) and 13(92.9%) students were rhesus negative male and female students respectively. One hundred and thirty five (73.8%), 36(19.7%) and 12(6.5%) of the sampled student population belonged to 17-20, 21-24 and 25-30yr age brackets respectively. One hundred and ten (60.1%), 38(20.8%), 29(15.9%) and 6(3.3%) students were of O, A, B and AB blood phenotypes respectively. Out of the 183 blood samples obtained from 93 (50.8%) and 90(49.2%) male and female students respectively, 126(68.9%) students were infected with P. falciparum malaria parasites. More males were infected than females and were significantly associated with malaria infection (X 2 0.05, 1 =3.841, Cal. X 2 =25.253, P˂0.05). Also, out of the 68.9% infected students, 47(37.3%) and 79(62.7%) had severe and non-severe forms of malaria infection respectively. Severe malaria frequency occurrences were 85.0%, 70.6%, 50.0% and 50.0% for blood types A, O, B and AB respectively while non-severe malaria frequency occurrences were 83.3%, 75.0%, 65.8% and 57.9% with respect to blood types A, AB O and B respectively. ABO blood types especially type A were significantly associated with severe form of P. falciparum malaria infection (X 2 0.05, 3 =7.815, X 2 0.01, 3 =11.350, Cal. X 2 =284.601 and P˂0.05, P˂0.01). ABO blood types were also significantly associated with non-severe form of malaria especially type A (Cal. X 2 =230.768 and hence, P˂0.05, P˂0.01). Implications of rising trend of rhesus negative factor in female students, population variations in association with ABO blood types and malaria parasitaemia are discussed.

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“…The adherence of parasitized RBCs to other cells is central to the pathophysiology of severe malaria syndromes including cerebral malaria, respiratory failure, multi-organ failure, and death. Parasitized RBCs adhere to the vasculature through a process termed sequestration closely mimicking inflammatory leukocyte attachment [17].…”

mentioning

confidence: 99%

“…Individuals with blood group A and B are more susceptible to malaria infection as compared with individuals of blood group O; however the severity of infection differs due to differential host susceptibility [19][20]. On the other hand, many other reports demonstrated absence of significant association of all ABO blood groups with malaria, implying that all individuals with any type of blood group type are being equally susceptible to malaria [2,17,21].…”

mentioning

confidence: 99%

Prevalence and association of malaria with ABO blood group and hemoglobin levels in individuals visiting Mekaneeyesus Primary Hospital, Estie District, northwest Ethiopia: A cross-sectional study

Tazebew

Munshea

Nibret

2020

Preprint

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Background Malaria continues to be a major health problem in developing sub-Saharan countries including Ethiopia. Malaria is a complex disease and its local characteristics are determined by a variety of geographical, environmental, insect vector, host, and parasite factors.Methods A hospital based cross-sectional study was conducted to determine the prevalence of malaria and its possible association with hemoglobin level and ABO blood group among individuals attending Mekaneeyesus Primary Hospital, Estie District, northwestern Ethiopia. Socio-demographic variables and relevant data were collected from 390 randomly selected individuals through structured questionnaire. Then, thick and thin smears were prepared from finger pricked blood samples, stained, and examined microscopically for detection and identification of malaria parasites. ABO blood group and hemoglobin levels of the same subjects were also determined. The data generated were entered into a computer and analyzed for descriptive and logistic regression models using SPSS version 23.0. Variables with p-value < 0.05 in multivariable logistic regression were considered as explanatory variables.Results The overall prevalence of malaria was 8.5%; Plasmodium vivax (5.6%) was the most predominant, followed by P. falciparum (2.3%), and mixed infection of the two species (0.5%). In multivariate logistic regression analysis, being male (AOR = 3.48), under-five years of age (AOR = 72.84), rural residence (AOR = 2.64), and failing to use bed net (AOR =4.65) were significantly associated with the risk of malaria infection. Most (14.6%) of malaria positives cases were among individuals with blood group “A”, while the least number of cases were among subjects with blood group “O”. Individuals with blood group “A” were about four times more likelihood of getting malaria as compared to individuals with blood group “O” (AOR= 3.74). The prevalence of anemia was 23% and significantly associated with malaria (p<0.05).Conclusions Malaria in the study area is still higher than the average prevalence at country level. Therefore special attention should be given to the prevention and control strategies with the objective of increasing the awareness of local community towards malaria.

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Malaria Parasitaemia Association with ABO Blood Types among Students of a Private University in Western Delta, Nigeria

Cited by 6 publications

References 37 publications

A Study on The Prevalence of ABO Blood Groups in Malaria Infection

A Study on The Prevalence of ABO Blood Groups in Malaria Infection

Abo Blood Variants of Selected Babcock University Students and Their Link with Malaria Parasitaemia

Prevalence and association of malaria with ABO blood group and hemoglobin levels in individuals visiting Mekaneeyesus Primary Hospital, Estie District, northwest Ethiopia: A cross-sectional study

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