Malaria outbreak investigation - Mopani and Vhembe districts, Limpopo province, South Africa, May 2017

Ravhuhali, Khuliso Goodman; Ramalwa, Ntsieni; Reddy, Carl

doi:10.11604/pamj.cp.2017.3.91.220

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“…The first outbreak which was mainly concentrated in KwaZulu-Natal province occurred in early 2000 where over 60,000 cases were recorded [ 1 ]. The most recent malaria outbreak was reported in 2017, when over 28,000 cases were recorded in South Africa with Limpopo province accounting for majority of new malaria transmissions [ 2 , 3 ]. These sporadic malaria outbreaks continue to be a large public health concern.…”

Section: Introductionmentioning

confidence: 99%

Investment case for malaria elimination in South Africa: a financing model for resource mobilization to accelerate regional malaria elimination

Njau¹,

Silal

Kollipara

et al. 2021

Malar J

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Background Malaria continues to be a public health problem in South Africa. While the disease is mainly confined to three of the nine provinces, most local transmissions occur because of importation of cases from neighbouring countries. The government of South Africa has reiterated its commitment to eliminate malaria within its borders. To support the achievement of this goal, this study presents a cost–benefit analysis of malaria elimination in South Africa through simulating different scenarios aimed at achieving malaria elimination within a 10-year period. Methods A dynamic mathematical transmission model was developed to estimate the costs and benefits of malaria elimination in South Africa between 2018 and 2030. The model simulated a range of malaria interventions and estimated their impact on the transmission of Plasmodium falciparum malaria between 2018 and 2030 in the three endemic provinces of Limpopo, Mpumalanga and KwaZulu-Natal. Local financial, economic, and epidemiological data were used to calibrate the transmission model. Results Based on the three primary simulated scenarios: Business as Usual, Accelerate and Source Reduction, the total economic burden was estimated as follows: for the Business as Usual scenario, the total economic burden of malaria in South Africa was R 3.69 billion (USD 223.3 million) over an 11-year period (2018–2029). The economic burden of malaria was estimated at R4.88 billion (USD 295.5 million) and R6.34 billion (~ USD 384 million) for the Accelerate and Source Reduction scenarios, respectively. Costs and benefits are presented in midyear 2020 values. Malaria elimination was predicted to occur in all three provinces if the Source Reduction strategy was adopted to help reduce malaria rates in southern Mozambique. This could be achieved by limiting annual local incidence in South Africa to less than 1 indigenous case with a prediction of this goal being achieved by the year 2026. Conclusions Malaria elimination in South Africa is feasible and economically worthwhile with a guaranteed positive return on investment (ROI). Findings of this study show that through securing funding for the proposed malaria interventions in the endemic areas of South Africa and neighbouring Mozambique, national elimination could be within reach in an 8-year period.

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Section: Introductionmentioning

confidence: 99%