Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple <i>Plasmodium falciparum</i> infections

Saúte, Francisco; Menéndez, Clara; Mayor, Alfredo; Aponte, John J.; Gómez-Olivé, Xavier; Dgedge, Martinho; Alonso, Pedro L.

doi:10.1046/j.1365-3156.2002.00831.x

Cited by 72 publications

(80 citation statements)

References 37 publications

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“…The first range started among 15-19 through 44. The highest prevalence was found among the age group 15-19 years which is in accordance with the previous report that age may be independent risk factors, as younger pregnant women have been found to be more susceptible to malaria in some settings [10]. Furthermore, adolescent and young adult women have been observed to have higher incidence of parasitaemia than older adults.…”

Section: Discussionsupporting

confidence: 90%

Evaluation of the use of Intermittent Preventive Therapy and Long Lasting Insecticidal Nets for Malaria Prevalence among Pregnant Women in Nkpor, Nigeria

Nwachukwu¹

2018

PPIJ

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A study on the use of intermittent preventive therapy (IPT) and Long lasting insecticidal nets (LLINs) for malaria prevalence among pregnant women in Nkpor, Anambra State, Nigeria between May and July 2015. A total number of 176 pregnant women were examined microscopically using their peripheral blood for malaria parasites. A structured questionnaire was used to determine the usage of LLINs and compliance to ITP. The result showed 51.7 %( 91/179) of the women were positive for malaria parasites. Malaria prevalence on the use of IPT was 54.5% (96/176) while the use of LLINs was 43.8% (77/176). The prevalence among primigravidae was 64.9% (50/77) and multigravidae was 41.1% (41/99). The use of LLINs has lower malaria prevalence than the use of IPT for malaria among pregnant women. Malaria is high among pregnant women and control efforts need to be improved urgently in Nkpor, Nigeria.

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Section: Discussionsupporting

confidence: 90%

Evaluation of the use of Intermittent Preventive Therapy and Long Lasting Insecticidal Nets for Malaria Prevalence among Pregnant Women in Nkpor, Nigeria

Nwachukwu¹

2018

PPIJ

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“…Moreover, infections at densities below the limit of microscopic detection (submicroscopic infections) contribute to the underestimation of the actual burden of P. falciparum infection among pregnant women in areas where malaria is endemic (25,28,37). The PCR method has the potential to overcome these limitations by providing a more sensitive estimate of maternal infections (44).…”

Section: Sequestration Of Erythrocytes Infected By Mature Forms Ofmentioning

confidence: 99%

Persistence of Plasmodium falciparum Parasites in Infected Pregnant Mozambican Women after Delivery

et al. 2011

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“…19,[22][23][24] The number of genotypes has been found to decrease with gravidity in some studies, 23,24 but not in others. 19,25 In Ngali II, women were bitten at least once every other day by an infected mosquito. It is therefore not surprising that the repertoire of multiple parasite genotypes changed constantly during pregnancy ( Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

“…19,20 This assay is a standard approach for studying genetic diversity of P. falciparum , 18,20 including in pregnant women. 19,[21][22][23][24][25] The number of alleles at the two loci was determined and the locus with the largest number of bands was used to estimate the MoI. In addition, the C-terminus of MSP-1 was sequenced and the MSP1-19 type was determined based on amino acids at position 294, 341, 349, 350, 351, and 366 of the MSP-1 42 3D7 reference sequence.…”

Section: Study Population Between January 2001 and May 2005mentioning

confidence: 99%

Longitudinal Studies of Plasmodium falciparum Malaria in Pregnant Women Living in a Rural Cameroonian Village with High Perennial Transmission

Leke

Bioga²,

Zhou³

et al. 2010

The American Journal of Tropical Medicine and Hygiene

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Abstract. A prospective longitudinal study of Plasmodium falciparum in pregnant women was conducted in the rural village of Ngali II, where malaria is hyperendemic and individuals receive ~0.7 infectious mosquito bites/person/day throughout the year. Pregnant women ( N = 60; 19 primigravidae, 41 multigravidae) were enrolled early in pregnancy (median 14 wk) and were followed monthly, with 38 women followed through term (5.7 ± 1.1 prenatal visits and delivery). The total number of times primigravidae were slide-positive during pregnancy was higher than multigravidae (3.3 ± 1.1 versus 1.3 ± 1.3 times; P < 0.001), but no difference in the number of polymerase chain reaction-positive cases (4.6 ± 1.7 and 3.4 ± 1.7 times, P = 0.106) or total genotypes they harbored (8.9 ± 3.2 and 7.0 ± 2.9) was found. Only 7.9% women developed symptomatic infections. All primigravidae and 38% multigravidae were placental malaria-positive at delivery ( P = 0.009). Genotyping showed that 77% of placental parasites were acquired ≥ 30 wks in pregnancy. These results help identify the extent of malaria-associated changes women experience during pregnancy.

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Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple Plasmodium falciparum infections

Cited by 72 publications

References 37 publications

Evaluation of the use of Intermittent Preventive Therapy and Long Lasting Insecticidal Nets for Malaria Prevalence among Pregnant Women in Nkpor, Nigeria

Evaluation of the use of Intermittent Preventive Therapy and Long Lasting Insecticidal Nets for Malaria Prevalence among Pregnant Women in Nkpor, Nigeria

Persistence of Plasmodium falciparum Parasites in Infected Pregnant Mozambican Women after Delivery

Longitudinal Studies of Plasmodium falciparum Malaria in Pregnant Women Living in a Rural Cameroonian Village with High Perennial Transmission

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