Malaria in a Liver Transplant Recipient: A Case Report

Mejia, Gonzalo; Álvarez, Carlos A.; Pulido, Hannier; Ramírez, Bertha Cárdenas; Cardozo, Celia; Suárez, Y. Fundora; Lobelo, Rafael; Sarquis, Teresita; Uribe, Alexander

doi:10.1016/j.transproceed.2006.08.187

Cited by 21 publications

(15 citation statements)

References 6 publications

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“…Several cases of malaria in organ transplant recipients have been described in the literature, with the majority of cases involving renal transplant patients. At least 45 cases have been identified in total: 36 in renal transplant patients (24,55,92,147,174,183,198,223,224,270,372,410), 6 in liver transplant patients (89,243,356), and 3 in the context of cardiac transplantation (17). Upon analysis of the data available in the literature, P. falciparum was identified as the infecting species in the majority of cases (21 cases), there were 13 cases due to P. vivax, 1 case due to P. ovale (hepatic transplant), and 1 case of P. malariae in a renal transplant patient.…”

Section: Routes Of Transmissionmentioning

confidence: 99%

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

et al. 2008

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SUMMARY In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included.

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Section: Routes Of Transmissionmentioning

confidence: 99%

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

et al. 2008

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“…Even with the use of the most sensitive diagnostic test on blood, liver transplantation has been associated with the transmission of P. vivax due to the persistence of hepatic hypnozoites, which is also possible for P. ovale [112,113]. Several cases of multi-organ transmission of malaria from a single donor have been described [107,114,115].…”

Section: Donor Deferral and Screeningmentioning

confidence: 99%

Chagas Disease, Leishmaniasis, and Malaria in Solid Organ Transplant Recipients

Antinori¹,

Milazzo²

2018

obm transplant

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Solid organ transplantation (SOT) is increasingly employed worldwide to treat several diseases causing both acute and chronic organ failure. Recipients of SOT are at an increased risk to develop infections as a consequence of immunosuppressive therapy. Sometimes such infections may be acquired by the transplanted organ or by reactivation of a previously acquired latent infection. The globalization and the increase of international travel poses a risk for exposure to infections such as Chagas disease (CD), leishmaniasis, and malaria endemic in tropical and subtropical areas of the world. We have reviewed the literature regarding risk factors, clinical presentation, diagnosis, and treatment of CD, leishmaniasis, and malaria in the setting of SOT.

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“…Malaria may also be transmitted by contaminated blood products and even via organ donation. In addition to the transfer of parasitized erythrocytes within transplanted organs, Plasmodium ovale and Plasmodium vivax , due to their persistence in hepatocytes, can be transmitted through liver transplantation 34 . The development of malaria in SOTRs is rare and usually occurs in individuals that have undergone organ transplantation in a malaria endemic area or received organs from a donor who has traveled or resided in an area of malaria endemicity.…”

Section: Parasitesmentioning

confidence: 99%