Malaria - Diagnostics Today

Chander, Yogesh; Nagendra, A; Subramanya, H

doi:10.1016/s0377-1237(01)80038-1

Cited by 1 publication

(3 citation statements)

References 18 publications

(11 reference statements)

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“…Subjectivity, need for considerable expertise for interpretation and delays associated with it are unavoidable. This historically important method, though not very sensitive and reproducible, has been accorded the status of "gold standard" [4]. Various attempts have been made to improve the sensitivity and specificity of smear examination.…”

Section: Discussionmentioning

confidence: 99%

“…The degree of parasitemia varies with phases in the life cycle of the parasite as well as the vector. Many a times the parasites remain sequestered and are not present in peripheral blood [4]. Best results are achieved when the time of specimen collection is in tandem with peripheral parasitemia.…”

Section: Discussionmentioning

confidence: 99%

“…Besides technical difficulties, examining a bad smear leads to frustration and lowered efficiency of the laboratory technician. Diagnosis of malaria by smear examination is considered to be cost effective [4]. However, if the cost of trained manpower, establishment of infrastructure, delayed diagnosis/missed diagnosis leading to avoidable morbidity and mortality is taken into account then this method does not remain cost effective or cheap at all.…”

Section: Discussionmentioning

confidence: 99%

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Saving Private Ryan: The Indian Scenario (Rapid Diagnosis of Malaria at Regimental Aid Post)

Gokhale

2004

Medical Journal Armed Forces India

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Immunochromatography test (ICT) (Paracheck Pf) for diagnosis of Plasmodium falciparum (Pf) infection was compared with the conventional smear examination method. A total of 350 specimens of blood from cases of fever were investigated (falciparum malaria 220, vivax malaria 100, controls 30). Paracheck Pf ICT was found to have enormous advantages over smear examination due to its high degree of sensitivity, specificity, speed and ease of performance. Paracheck Pf ICT test kits are stable at room temperature. Regimental medical officers (RMOs) and nursing assistants with minimal training can safely practise Paracheck Pf ICT method. Introduction of this test method in the Armed Forces can facilitate early diagnosis and specific treatment of falciparum malaria even at far flung places. This will have enormous beneficial effect in reducing morbidity due to malaria and saving precious lives. In short as well as long term, it is a viable cost effective option. MJAFI 2004; 60 : 137-141

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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