Malakoplakia of Lung in an Immunocompromised Patient

Tewari, S C; Chatterji, R.; Sj, Varghese; Prasad, B. R.; Garg, Aditya

doi:10.1016/s0377-1237(01)80097-6

Cited by 1 publication

(3 citation statements)

References 6 publications

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“…Tewari et al 5 found that most infections leading to malakoplakia were caused by E. coli and R. equi . Other bacteria include Klebsiella , Corynebacterium , Staphylococcus aureus , and Mycobacteria species (including tuberculosis) 5 …”

Section: Discussionmentioning

confidence: 99%

“…Other bacteria include Klebsiella, Corynebacterium, Staphylococcus aureus, and Mycobacteria species (including tuberculosis). 5 Tuberculosis resulted in a HIV-positive patient developing pulmonary malakoplakia. 6,17 Pulmonary malakoplakia can stimulate tumors and mimic tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

“…Malakoplakia has been reported in HIV-positive patients in the genitourinary tract, genitals, lungs, and scalp 16 . Tewari et al 5 found that most infections leading to malakoplakia were caused by E. coli and R. equi . Other bacteria include Klebsiella , Corynebacterium , Staphylococcus aureus , and Mycobacteria species (including tuberculosis) 5 …”

Section: Discussionmentioning

confidence: 99%

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Vaginal Malakoplakia

Patel

Maller

Abraham³

et al. 2021

Infectious Diseases in Clinical Practice

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Malakoplakia is a rare chronic inflammatory disease that predominantly develops in the urogenital system. Although its clinical presentation can vary from asymptomatic to urgent depending on location, mass effect, and other factors, its gross appearance can be mistaken for malignancy. However, the histological identification of von Hansemann histiocytes and Michaelis-Gutmann bodies confirm the diagnosis of malakoplakia. We present a case of a female patient who sought medical care for acute pelvic discomfort attributed to urinary retention after urinary obstruction. Although the discovery of multiple masses within the vagina and pelvic cavity indicated a tumor, it was originally negative for malignancy. Histology of biopsy samples demonstrated Michaelis-Gutmann bodies mixed with lymphoid cells through immunohistochemical and periodic acid-Schiff stains, consistent with a diagnosis of malakoplakia. Despite negative cultures, multiple courses of antibiotics were given, but the mass progressed and caused urinary obstruction. After pelvic exenteration, lymphoma was diagnosed and treated. We review the current literature on malakoplakia in different body sites associated with infections and noninfectious diseases.

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Section: Discussionmentioning

confidence: 99%