Maladies systémiques et infections virales : étude de 95 observations

Diallo, S.; Mbengue, M.; Diallo, R.; Diaw, C.A.B.; Niasse, Moustapha; Diouf, C.

doi:10.1016/s1169-8330(16)30336-2

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“…The patient also has a hepatitis B infection that is often implicated in the occurrence of autoimmune diseases. Diallo andcol [9] reported a case of scleroderma associated with secondary Sjögren's syndrome in their series. In this case, the role of HIV, hepatitis B or both antigens in the development of scleroderma remains uncertain.…”

Section: Discussionmentioning

confidence: 99%

Scleroderma and HIV Infection: A Case Report with Literature Review

Dembele¹,

Nyanke²,

Traore³

et al. 2018

OJIM

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Introduction: Acquired immunodeficiency syndrome (AIDS) linked to HIV infection is accompanied by auto-immune phenomena. Autoimmune diseases can develop in people living with HIV, most in a context of good immunological control (vasculitis, anti-phospholipid syndrome). Since the advent of antiretroviral therapy, an increasing number of autoimmune connective tissue diseases such as systemic lupus erythematosus, dermatomyositis, and syndromes of Sjögren and scleroderma have been reported. Purpose: To describe this association's not very common scleroderma and HIV infection. Observation: We report the case of a 56-year-old lady admitted into the service for functional impotence that would have been evolving for a week. Prior to her hospitalization, she presented edemas of the lower limbs associated with anesthesia of the lower limbs for 5 months. The painting is accompanied by a productive cough and an intermittent fever. At the physical examination a weight loss (BMI = 13.74 Kg/m²), fever (38.7˚C): Oral candidiasis, lower lip ulceration, perlicking, undernutrition folds, sclerodactyly and homogeneous hepatomegaly was noted. The diagnosis of immunosuppression to HIV Stage 3 with TB co-morbidity and positive hepatitis B Serology was retained while diffuse Scleroderma was selected from the ACR/EULAR criteria of 2012 with a score of 10 (sclerodactyly = 4 point; Raynaud's phenomenon = 3 point and Ac Anti Scl 70 positive = 3 point). Conclusion: These associations of chronic pathology must be described to improve the future treatment of our patients.

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Section: Discussionmentioning

confidence: 99%