Making the Case for Hyperosmolar Saline Arthroscopic Irrigation Fluids: A Systematic Review of Basic Science, Translational, and Clinical Evidence
Lasun O. Oladeji,
Aaron M. Stoker,
Keiichi Kuroki
et al.
Abstract:Introduction: Commonly used isotonic arthroscopic irrigation fluids, such as normal saline or lactated Ringer’s, were initially formulated for intravenous administration so they do not replicate the physiologic properties of healthy synovial fluid. Synovial fluid plays an important role in regulating joint homeostasis so even transient disruptions in joint physiology can be impactful. Previous studies suggest that hyperosmolar solutions may be a promising alternative to traditional isotonic fluids. This manusc… Show more
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